BS60789
antibody from Bioworld Technology, Inc
Targeting: PLXNA4
DKFZp434G0625PRO34003, FAYV2820, KIAA1550, PLXNA4A, PLXNA4B
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS60789 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- PLXNA4 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human PLXNA4.
- Description
- Plexin-A4, also known as PLXNA4 or FAYV2820, is a 1,894 amino acid singlepass type I membrane protein that contains one sema domain, three PSI domains and four IPT/TIG domains. Belonging to a large family of semaphorin (SEMA) receptors, plexin-A4 forms a complex with neuropilin and, once complexed, can propagate SEMA3A-induced inhibitory signals into neurons and cells, possibly playing a role in early nerve development. Four isoforms of plexin-A4 exist due to alternative splicing events. The gene encoding plexin-A4 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome.
- Reactivity
- Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of PLXNA4 pAb at 1:500 dilutionLane1:sp2/0 whole cell lysate Lane2:PC12 whole cell lysate