Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- ABIN2847128 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-AKT1 Substrate 1 (Proline-Rich) (AKT1S1) (AA 227-256), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 227-256, C-Term
- Antibody clone number
- RB34859
- Vial size
- 80 μL
- Storage
- AKT1S1 Antibody (C-term) can be refrigerated at 2-8°C for up to 6 months. For long term storage, place the at -20°C.
Submitted references Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation.
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.
PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding.
Wang L, Harris TE, Lawrence JC Jr
The Journal of biological chemistry 2008 Jun 6;283(23):15619-27
The Journal of biological chemistry 2008 Jun 6;283(23):15619-27
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.
Sancak Y, Thoreen CC, Peterson TR, Lindquist RA, Kang SA, Spooner E, Carr SA, Sabatini DM
Molecular cell 2007 Mar 23;25(6):903-15
Molecular cell 2007 Mar 23;25(6):903-15
PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding.
Wang L, Harris TE, Roth RA, Lawrence JC Jr
The Journal of biological chemistry 2007 Jul 6;282(27):20036-44
The Journal of biological chemistry 2007 Jul 6;282(27):20036-44
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