11-7010-25

antibody from ABEOMICS Inc.
Targeting: H2AX H2AFX
Provider product page for 11-7010-25

Antibody data

Product number
11-7010-25 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-Histone H2A.x Antibody
Antibody type
Polyclonal
Description
Histones are major chromatin proteins that wrap DNA to form nucleosome particles. Each nucleosome core particle consists of approximately 146 bp DNA wrapped by an octamer containing 2 molecules each of histones H2A, H2B, H3, and H4. Histone H1 sits on the linker DNA between nucleosomes. Their major function is to compact long DNA strands inside the nucleus and chromatin regulation. Histone H2A X is a 15 kDa variant of Histone H2. Histone H2A X is also required for the repair of double-stranded DNA breaks particularly when modified by C-terminal phosphorylation on Ser-140. Histone H2A X is expressed in all eukaryotic cells.
Reactivity
Human
Host
Rabbit
Antigen sequence
Full length recombinant Histone H2A
.x protein was used as the immunoge
n for this antibody.
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
H2AX protein structure - 11-7010-25 shown in red.