Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS61150 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- CPXM2 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human CPXM2.
- Description
- Members of the M14 metallocarboxypeptidase protein family serve many diverse functions and are divided into three subfamilies based on structure, function and amino acid sequence similarity. Belonging to the N/E subfamily, CPXM2 (Inactive carboxypeptidase-like protein X2) is a 756 amino acid protein that contains a F5/8 type C domain and is secreted. Most members of the N/E subfamily contain several domains, including an active carboxypeptidase domain and signal peptide and are thought to function mostly in mediating protein-protein interactions and/or protein-membrane interactions, thereby targeting the protein to specific locations within the secretory pathway. CPXM2 is a unique member of this subfamily in that it does not appear to exhibit any enzymatic activity due to lack of several active-site residues that are present in the catalytic domain of other members of the N/E subfamily. Expression of the closely related protein CPXM is regulated during osteoclastogenesis, suggesting that CPXM may play a role in osteoclast differentiation.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of CA8 pAb at 1:500 Line1:Mcf-7 whole cell lysateLine2:H9C2 whole cell lysateLine3:sp20 whole cell lysate