Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
- Flow cytometry [1]
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Validation data
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- Product number
- ABIN258615 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-KIAA1524 (KIAA1524) (C-Term) antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Mouse
- Epitope
- C-Term
- Isotype
- IgG
- Antibody clone number
- 2G10
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references MicroRNA-383-5p acts as a prognostic marker and inhibitor of cell proliferation in lung adenocarcinoma by cancerous inhibitor of protein phosphatase 2A.
CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations.
CIP2A is overexpressed in osteosarcoma and regulates cell proliferation and invasion.
miR-375 activates p21 and suppresses telomerase activity by coordinately regulating HPV E6/E7, E6AP, CIP2A, and 14-3-3ζ.
CIP2A facilitates apoptotic resistance of fibroblast-like synoviocytes in rheumatoid arthritis independent of c-Myc expression.
Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interactions.
CIP2A expression is associated with synovial hyperplasia and invasive function of fibroblast-like synoviocytes in rheumatoid arthritis.
Overexpression and small molecule-triggered downregulation of CIP2A in lung cancer.
CIP2A is over-expressed in acute myeloid leukaemia and associated with HL60 cells proliferation and differentiation.
CIP2A is overexpressed in gastric cancer and its depletion leads to impaired clonogenicity, senescence, or differentiation of tumor cells.
Cloning and characterization of a novel 90 kDa 'companion' auto-antigen of p62 overexpressed in cancer.
Zhao S, Gao X, Zang S, Li Y, Feng X, Yuan X
Oncology letters 2017 Sep;14(3):3573-3579
Oncology letters 2017 Sep;14(3):3573-3579
CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations.
Khanna A, Rane JK, Kivinummi KK, Urbanucci A, Helenius MA, Tolonen TT, Saramäki OR, Latonen L, Manni V, Pimanda JE, Maitland NJ, Westermarck J, Visakorpi T
Oncotarget 2015 Aug 14;6(23):19661-70
Oncotarget 2015 Aug 14;6(23):19661-70
CIP2A is overexpressed in osteosarcoma and regulates cell proliferation and invasion.
Zhai M, Cong L, Han Y, Tu G
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Feb;35(2):1123-8
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Feb;35(2):1123-8
miR-375 activates p21 and suppresses telomerase activity by coordinately regulating HPV E6/E7, E6AP, CIP2A, and 14-3-3ζ.
Jung HM, Phillips BL, Chan EK
Molecular cancer 2014 Apr 8;13:80
Molecular cancer 2014 Apr 8;13:80
CIP2A facilitates apoptotic resistance of fibroblast-like synoviocytes in rheumatoid arthritis independent of c-Myc expression.
Lee J, Jeong H, Park EJ, Hwang JW, Huang B, Bae EK, Ahn JK, Cha HS, Koh EM
Rheumatology international 2013 Sep;33(9):2241-8
Rheumatology international 2013 Sep;33(9):2241-8
Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interactions.
Jung HM, Patel RS, Phillips BL, Wang H, Cohen DM, Reinhold WC, Chang LJ, Yang LJ, Chan EK
Molecular biology of the cell 2013 Jun;24(11):1638-48, S1-7
Molecular biology of the cell 2013 Jun;24(11):1638-48, S1-7
CIP2A expression is associated with synovial hyperplasia and invasive function of fibroblast-like synoviocytes in rheumatoid arthritis.
Lee J, Park EJ, Hwang JW, Oh JM, Kim H, Bae EK, Choi YL, Han J, Ahn JK, Cha HS, Koh EM
Rheumatology international 2012 Jul;32(7):2023-30
Rheumatology international 2012 Jul;32(7):2023-30
Overexpression and small molecule-triggered downregulation of CIP2A in lung cancer.
Ma L, Wen ZS, Liu Z, Hu Z, Ma J, Chen XQ, Liu YQ, Pu JX, Xiao WL, Sun HD, Zhou GB
PloS one 2011;6(5):e20159
PloS one 2011;6(5):e20159
CIP2A is over-expressed in acute myeloid leukaemia and associated with HL60 cells proliferation and differentiation.
Wang J, Li W, Li L, Yu X, Jia J, Chen C
International journal of laboratory hematology 2011 Jun;33(3):290-8
International journal of laboratory hematology 2011 Jun;33(3):290-8
CIP2A is overexpressed in gastric cancer and its depletion leads to impaired clonogenicity, senescence, or differentiation of tumor cells.
Li W, Ge Z, Liu C, Liu Z, Björkholm M, Jia J, Xu D
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Jun 15;14(12):3722-8
Clinical cancer research : an official journal of the American Association for Cancer Research 2008 Jun 15;14(12):3722-8
Cloning and characterization of a novel 90 kDa 'companion' auto-antigen of p62 overexpressed in cancer.
Soo Hoo L, Zhang JY, Chan EK
Oncogene 2002 Jul 25;21(32):5006-15
Oncogene 2002 Jul 25;21(32):5006-15
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Supportive validation
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- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS