Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [3]
- Immunohistochemistry [4]
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- Product number
- NB100-74663 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-74663, RRID:AB_1048571
- Product name
- Rabbit Polyclonal CIP2A Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C. Do not freeze.
Submitted references DAPK and CIP2A are involved in GAS6/AXL-mediated Schwann cell proliferation in a rat model of bilateral cavernous nerve injury.
Overexpression of epithelial cell transforming 2 protein in colorectal carcinoma predicts a poor prognosis.
Cellular localization of CIP2A determines its prognostic impact in superficial spreading and nodular melanoma.
Cancerous inhibitor of protein phosphatase 2A (CIP2A) is an independent prognostic marker in wild-type KRAS metastatic colorectal cancer after colorectal liver metastasectomy.
Temsirolimus enhances the efficacy of cetuximab in colon cancer through a CIP2A-dependent mechanism.
CIP2A is highly expressed in hepatocellular carcinoma and predicts poor prognosis.
CIP2A is a predictor of poor prognosis in colon cancer.
Prognostic role of CIP2A expression in serous ovarian cancer.
CIP2A expression is increased in prostate cancer.
CIP2A increases self-renewal and is linked to Myc in neural progenitor cells.
Chen YL, Tsai YT, Chao TT, Wu YN, Chen MC, Lin YH, Liao CH, Chou SP, Chiang HS
Oncotarget 2018 Jan 19;9(5):6402-6415
Oncotarget 2018 Jan 19;9(5):6402-6415
Overexpression of epithelial cell transforming 2 protein in colorectal carcinoma predicts a poor prognosis.
Li Y, Cai X, Chen B, Gu H, Liu C
Experimental and therapeutic medicine 2017 Nov;14(5):4862-4868
Experimental and therapeutic medicine 2017 Nov;14(5):4862-4868
Cellular localization of CIP2A determines its prognostic impact in superficial spreading and nodular melanoma.
Flørenes VA, Emilsen E, Dong HP, Førsund M, Holm R, Slipicevic A
Cancer medicine 2015 Jun;4(6):903-13
Cancer medicine 2015 Jun;4(6):903-13
Cancerous inhibitor of protein phosphatase 2A (CIP2A) is an independent prognostic marker in wild-type KRAS metastatic colorectal cancer after colorectal liver metastasectomy.
Chen KF, Yen CC, Lin JK, Chen WS, Yang SH, Jiang JK, Lan YT, Lin CC, Yu HC, Hsu HM, Lin WL, Teng HW
BMC cancer 2015 Apr 17;15:301
BMC cancer 2015 Apr 17;15:301
Temsirolimus enhances the efficacy of cetuximab in colon cancer through a CIP2A-dependent mechanism.
Wang HW, Yang SH, Huang GD, Lin JK, Chen WS, Jiang JK, Lan YT, Lin CC, Hwang WL, Tzeng CH, Li AF, Yen CC, Teng HW
Journal of cancer research and clinical oncology 2014 Apr;140(4):561-71
Journal of cancer research and clinical oncology 2014 Apr;140(4):561-71
CIP2A is highly expressed in hepatocellular carcinoma and predicts poor prognosis.
He H, Wu G, Li W, Cao Y, Liu Y
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2012 Sep;21(3):143-9
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2012 Sep;21(3):143-9
CIP2A is a predictor of poor prognosis in colon cancer.
Teng HW, Yang SH, Lin JK, Chen WS, Lin TC, Jiang JK, Yen CC, Li AF, Chen PC, Lan YT, Lin CC, Hsu YN, Wang HW, Chen KF
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2012 May;16(5):1037-47
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2012 May;16(5):1037-47
Prognostic role of CIP2A expression in serous ovarian cancer.
Böckelman C, Lassus H, Hemmes A, Leminen A, Westermarck J, Haglund C, Bützow R, Ristimäki A
British journal of cancer 2011 Sep 27;105(7):989-95
British journal of cancer 2011 Sep 27;105(7):989-95
CIP2A expression is increased in prostate cancer.
Vaarala MH, Väisänen MR, Ristimäki A
Journal of experimental & clinical cancer research : CR 2010 Oct 21;29(1):136
Journal of experimental & clinical cancer research : CR 2010 Oct 21;29(1):136
CIP2A increases self-renewal and is linked to Myc in neural progenitor cells.
Kerosuo L, Fox H, Perälä N, Ahlqvist K, Suomalainen A, Westermarck J, Sariola H, Wartiovaara K
Differentiation; research in biological diversity 2010 Jul;80(1):68-77
Differentiation; research in biological diversity 2010 Jul;80(1):68-77
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CIP2A Antibody [NB100-74663] - CIP2A downregulation reduces proliferation and induces apoptosis in melanoma cells. Immunoblot analysis showing reduction in cancerous inhibitor of protein phosphatase 2A protein levels 48 h post siRNA transfection and effects on proliferation and apoptosis markers. The figure is representative of at last three independent biological experiments. Image collected and cropped by CiteAb from the following publication (http://doi.wiley.com/10.1002/cam4.425), licensed under a CC-BY licence.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CIP2A Antibody [NB100-74663] - Characterization of CIP2A expression in a panel of normal human melanocytes (NHM) and melanoma cell lines. Cytoplasmic and nuclear expression of CIP2A in normal melanocytes, primary and metastatic melanoma cell lines assessed by immunoblot analysis. CIP2A = cancerous inhibitor of protein phosphatase 2A. Image collected and cropped by CiteAb from the following publication (http://doi.wiley.com/10.1002/cam4.425), licensed under a CC-BY licence.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CIP2A Antibody [NB100-74663] - Characterization of CIP2A expression in a panel of normal human melanocytes (NHM) and melanoma cell lines. Immunoblot analysis of protein expression levels of CIP2A. Image collected and cropped by CiteAb from the following publication (http://doi.wiley.com/10.1002/cam4.425), licensed under a CC-BY licence.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: CIP2A Antibody [NB100-74663] - Section of human colon carcinoma. Antibody: Affinity purified rabbit anti-CIP2A used at a dilution of 1:100. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody used at a dilution of 1:100.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: CIP2A Antibody [NB100-74663] - Characterization of CIP2A expression in a panel of normal human melanocytes (NHM) and melanoma cell lines. Cytoplasmic and nuclear expression of CIP2A in normal melanocytes, primary and metastatic melanoma cell lines assessed by immunohistochemical staining. CIP2A = cancerous inhibitor of protein phosphatase 2A. Image collected and cropped by CiteAb from the following publication (http://doi.wiley.com/10.1002/cam4.425), licensed under a CC-BY licence.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CIP2A Antibody [NB100-74663] - Section of human colon carcinoma. Antibody: Affinity purified rabbit anti-CIP2A used at a dilution of 1:250. Detection: DAB
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CIP2A Antibody [NB100-74663] - Section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-CIP2A used at a dilution of 1:250. Detection: DAB