Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS61144 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- B4GALT2 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human B4GALT2.
- Description
- Several oligosaccharide structures and protein glycoconjugate types are found in nature. Homologous glycosyltransferase (GT) gene families catalyze the formation of glycosidic linkages. The beta-1,3 galactosyltransferase (ÉÇ-1,3-Gal-T) gene family encodes a set of type II transmembrane glycoproteins that are catalytically diverse and use different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine) to catalyze the addition of an activated monosaccharide to a terminal lactose. The protein coding sequences for ÉÇ-1,3-Gal-T genes comprise a single exon and are distantly related to the Drosophila Brainiac gene. The ÉÇ-1,4-galactosyltransferase (-1,4-Gal-T) gene family encodes type II membrane-bound glycoproteins that show exclusive specificity for the donor substrate, UDP-galactose. ÉÇ-1,4-Gal-T genes transfer galactose in a ÉÇ-1,4 linkage to similar acceptor sugars; each gene has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. GTs on the surface of sperm in part mediate gamete adhesion by binding to appropriate carbohydrate substrates in the egg zona pellucida. In several tissues and cell lines, GTs localize to the Golgi complex.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of B4GALT2 pAb at 1:500 dilutionLane1:A549 whole cell lysate Lane2:PC12 whole cell lysateLane3:SP20 whole cell lysate