BS9199

antibody from Bioworld Technology, Inc

Targeting: TESK2

Western blot (Data presented on provider website)

Antibody Data

Product number

BS9199

Provider

Bioworld Technology, Inc

Product name

TESK2 (F240) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide, corresponding to amino acids 210-256 of Human TESK2.

Description

TESK2 (testicular protein kinase 2) is a nuclear protein that belongs to the protein kinase superfamily and is expressed in testis and prostate. Functioning as a dual specificity protein kinase, TESK2 catalyzes the ATP-dependent phosphorylation of substrates and autophosphorylation on tyrosine and serine/ threonine residues, thereby mediating intracellular signal transduction pathways. TESK2 requires magnesium as a cofactor and its catalytic activity is thought to play an important role in meiotic events such as spermatogenesis.TESK2 contains one protein kinase domain that is 65% identical to the kinase domain found in TESK1 (testicular protein kinase 1), suggesting a similar role for these proteins in phosphorylation events. Three isoforms of TESK2 are expressed due to alternative splicing.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.