BS60656

antibody from Bioworld Technology, Inc
Targeting: TRMT11 C6orf75, dJ187J11.2, MDS024, TRM11, TRMT11-1
Provider product page for BS60656

Antibody data

Product number
BS60656 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TRMT11 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human TRMT11
Description
TRM11 (tRNA guanosine-2'-O-methyltransferase TRM11 homolog) is a 463 amino acid protein that belongs to the methyltransferase superfamily. TRM11 is believed to be the catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs. The gene encoding TRM11 maps to a region on chromosome 6 that is shared by seven other genes, which have been linked to diffuse panbronchiolitis. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TRMT11 protein structure - BS60656 shown in red.