BS8299

antibody from Bioworld Technology, Inc
Targeting: HGD AKU, HGO
Provider product page for BS8299
Western blot
Immunohistochemistry

Antibody data

Product number
BS8299 - Provider product page
Provider
Bioworld Technology, Inc
Product name
HGD polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human HGD.
Description
HGD (homogentisate 1,2-dioxygenase), also known as HGO (homogentisate oxygenase), is a 445 amino acid protein that belongs to the homogentisate dioxygenase family and is involved in the pathway of amino acid degradation. Expressed at high levels in kidney, colon, liver, prostate and small intestine, HGD uses iron as a cofactor to catalyze the oxygen-dependent conversion of homogentisate to 4-maleylacetoacetate, a reaction that is the fourth step in the creation of L-phenylalanine from fumarate and acetoacetic acid. Defects in the gene encoding HGD are the cause of alkaptonuria (AKU), an autosomal recessive disorder that is characterized by urine that turns dark on standing and alkalinization, black ochronotic pigmentation of cartilage and collagenous tissues and spine arthritis.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HGD protein structure - BS8299 shown in red.