Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- PAB13394 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB13394, RRID:AB_10550770
- Product name
- GP6 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of GP6.
- Storage
- Store at 4°C for three months. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Eltrombopag enhances platelet adhesion by upregulating the expression of glycoprotein VI in patients with chronic immune thrombocytopenic purpura.
Integrin alpha2beta1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCgamma2.
Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily.
The platelet collagen receptor glycoprotein VI is a member of the immunoglobulin superfamily closely related to FcalphaR and the natural killer receptors.
Chiou TJ, Chang YF, Wang MC, Kao CW, Lin HY, Chen TY, Hsueh EJ, Lan YJ, Sung YC, Lin SF, Bai LY, Chen CG
Translational research : the journal of laboratory and clinical medicine 2015 Dec;166(6):750-761.e4
Translational research : the journal of laboratory and clinical medicine 2015 Dec;166(6):750-761.e4
Integrin alpha2beta1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCgamma2.
Inoue O, Suzuki-Inoue K, Dean WL, Frampton J, Watson SP
The Journal of cell biology 2003 Mar 3;160(5):769-80
The Journal of cell biology 2003 Mar 3;160(5):769-80
Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily.
Jandrot-Perrus M, Busfield S, Lagrue AH, Xiong X, Debili N, Chickering T, Le Couedic JP, Goodearl A, Dussault B, Fraser C, Vainchenker W, Villeval JL
Blood 2000 Sep 1;96(5):1798-807
Blood 2000 Sep 1;96(5):1798-807
The platelet collagen receptor glycoprotein VI is a member of the immunoglobulin superfamily closely related to FcalphaR and the natural killer receptors.
Clemetson JM, Polgar J, Magnenat E, Wells TN, Clemetson KJ
The Journal of biological chemistry 1999 Oct 8;274(41):29019-24
The Journal of biological chemistry 1999 Oct 8;274(41):29019-24
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of GP6 in A-20 lysate with GP6 polyclonal antibody (Cat # PAB13394) at 1 ug/m in either the absence or (B) the presence of blocking peptide.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical staining of human heart tissue with 10 ug/mL GP6 polyclonal antibody (Cat # PAB13394).
- Validation comment
- Immunohistochemistry