FNab08519

antibody from FineTest Biotech
Targeting: TBCD
Provider product page for FNab08519
Western blot
ELISA
Immunoprecipitation

Antibody data

Product number
FNab08519 - Provider product page
Provider
FineTest Biotech
Product name
TBCD antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Tubulin-folding protein; involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin(TUBB). Acts as a GTPase-activating protein(GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
tubulin folding cofactor D
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
TBCD protein structure - FNab08519 shown in red.