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- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- PAB12411 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12411, RRID:AB_10553681
- Product name
- INSIG1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of INSIG1.
- Storage
- Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Sex differences in hepatic regulation of cholesterol homeostasis.
Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake.
Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.
De Marinis E, Martini C, Trentalance A, Pallottini V
The Journal of endocrinology 2008 Sep;198(3):635-43
The Journal of endocrinology 2008 Sep;198(3):635-43
Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake.
Gong Y, Lee JN, Lee PC, Goldstein JL, Brown MS, Ye J
Cell metabolism 2006 Jan;3(1):15-24
Cell metabolism 2006 Jan;3(1):15-24
Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.
Engelking LJ, Liang G, Hammer RE, Takaishi K, Kuriyama H, Evers BM, Li WP, Horton JD, Goldstein JL, Brown MS
The Journal of clinical investigation 2005 Sep;115(9):2489-98
The Journal of clinical investigation 2005 Sep;115(9):2489-98
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Western blot analysis of INSIG1 in HepG2 lyaste using INSIG1 polyclonal antibody (Cat # PAB12411).
