APR04583G

antibody from Leading Biology

Targeting: UBE3C KIAA0010, KIAA10

Western blot (Recommended by provider)

Antibody Data

Product number

APR04583G

Provider

Leading Biology

Product name

UBE3C Antibody (Center)

Antibody type

Polyclonal

Description

E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'-or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.

Reactivity

Human

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.