Tissue expression
Cell line expression
Protein structure
IL37
Interleukin 37FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 60296-1-Ig | 4 references | Monoclonal |
WB
EL
IHC
|
|
LSBio | LS-B10134 | Polyclonal |
WB
EL
ICC
IHC |
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Novus Biologicals | NBP2-14992 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
Invitrogen Antibodies | PA5-115405 | 1 references | Polyclonal |
WB
IHC
OA
|
|
NSJ Bioreagents | RQ6257 | Polyclonal |
EL
ICC
IHC
FC |
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Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider