AF1078
antibody from Novus Biologicals
Targeting: IL36A
FIL1, FIL1E, IL-1F6, IL1(EPSILON), IL1F6, MGC129552, MGC129553
Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- AF1078 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal IL-36 alpha/IL-1F6 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human IL-36 alpha/IL-1F6 in direct ELISAs and Western blots. In Western blots, less than 2% cross-reactivity with recombinant human (rh) rhIL-36 beta , rhIL-36 gamma , rhIL-1 alpha , rhIL-1 beta and rhIL-18 is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Interleukin-36 receptor mediates the crosstalk between plasma cells and synovial fibroblasts.
IL-1F5, -F6, -F8, and -F9: a novel IL-1 family signaling system that is active in psoriasis and promotes keratinocyte antimicrobial peptide expression.
Schmitt V, Hahn M, Kästele V, Wagner O, Wiendl M, Derer A, Taddeo A, Hahne S, Radbruch A, Jäck HM, Schuh W, Mielenz D, Gay S, Schett G, Hueber AJ, Frey S
European journal of immunology 2017 Dec;47(12):2101-2112
European journal of immunology 2017 Dec;47(12):2101-2112
IL-1F5, -F6, -F8, and -F9: a novel IL-1 family signaling system that is active in psoriasis and promotes keratinocyte antimicrobial peptide expression.
Johnston A, Xing X, Guzman AM, Riblett M, Loyd CM, Ward NL, Wohn C, Prens EP, Wang F, Maier LE, Kang S, Voorhees JJ, Elder JT, Gudjonsson JE
Journal of immunology (Baltimore, Md. : 1950) 2011 Feb 15;186(4):2613-22
Journal of immunology (Baltimore, Md. : 1950) 2011 Feb 15;186(4):2613-22
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human IL-36a/IL-1F6 by Western Blot. Detection of Human IL-36a/IL-1F6 by Western Blot.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- IL-36a/IL-1F6 in Human Tonsil. IL-36a/IL-1F6 in Human Tonsil.