Tissue expression
Cell line expression
Protein structure
CHMP2A
Charged multivesicular body protein 2ABC-2, CHMP2, VPS2, VPS2A
CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]). [supplied by OMIM, Mar 2008]
Top validated antibodies |
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Proteintech Group | ![]() |
45 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Invitrogen Antibodies | ![]() |
Polyclonal |
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Cusabio Biotech Co., Ltd | ![]() |
Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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