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Protein structure
ROR1
Receptor tyrosine kinase like orphan receptor 1NTRKR1
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]
Top validated antibodies |
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| Proteintech Group |  66923-1-Ig |
2 references | Monoclonal |
WB
EL
ICC
IHC
FC
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| Abnova Corporation | PAB3384 |
3 references | Polyclonal |
WB
IHC
FC
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| LSBio | LS-C99123 |
Polyclonal |
WB
IHC
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| R&D Systems | AF2000 |
12 references | Polyclonal |
WB
FC
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| Novus Biologicals | AF2000 |
12 references | Polyclonal |
WB
FC
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|
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