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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 16019-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16019-1-AP, RRID:AB_2230316
- Product name
- DBR1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DBR1 antibody (Cat. #16019-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection.
Identification of the specific interactors of the human lariat RNA debranching enzyme 1 protein.
Inhibition of U4 snRNA in human cells causes the stable retention of polyadenylated pre-mRNA in the nucleus.
Cell cycle regulation of microtubule interactomes: multi-layered regulation is critical for the interphase/mitosis transition.
Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models.
Zhang SY, Clark NE, Freije CA, Pauwels E, Taggart AJ, Okada S, Mandel H, Garcia P, Ciancanelli MJ, Biran A, Lafaille FG, Tsumura M, Cobat A, Luo J, Volpi S, Zimmer B, Sakata S, Dinis A, Ohara O, Garcia Reino EJ, Dobbs K, Hasek M, Holloway SP, McCammon K, Hussong SA, DeRosa N, Van Skike CE, Katolik A, Lorenzo L, Hyodo M, Faria E, Halwani R, Fukuhara R, Smith GA, Galvan V, Damha MJ, Al-Muhsen S, Itan Y, Boeke JD, Notarangelo LD, Studer L, Kobayashi M, Diogo L, Fairbrother WG, Abel L, Rosenberg BR, Hart PJ, Etzioni A, Casanova JL
Cell 2018 Feb 22;172(5):952-965.e18
Cell 2018 Feb 22;172(5):952-965.e18
Identification of the specific interactors of the human lariat RNA debranching enzyme 1 protein.
Masaki S, Yoshimoto R, Kaida D, Hata A, Satoh T, Ohno M, Kataoka N
International journal of molecular sciences 2015 Feb 9;16(2):3705-21
International journal of molecular sciences 2015 Feb 9;16(2):3705-21
Inhibition of U4 snRNA in human cells causes the stable retention of polyadenylated pre-mRNA in the nucleus.
Hett A, West S
PloS one 2014;9(5):e96174
PloS one 2014;9(5):e96174
Cell cycle regulation of microtubule interactomes: multi-layered regulation is critical for the interphase/mitosis transition.
Syred HM, Welburn J, Rappsilber J, Ohkura H
Molecular & cellular proteomics : MCP 2013 Nov;12(11):3135-47
Molecular & cellular proteomics : MCP 2013 Nov;12(11):3135-47
Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models.
Armakola M, Higgins MJ, Figley MD, Barmada SJ, Scarborough EA, Diaz Z, Fang X, Shorter J, Krogan NJ, Finkbeiner S, Farese RV Jr, Gitler AD
Nature genetics 2012 Dec;44(12):1302-9
Nature genetics 2012 Dec;44(12):1302-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 16019-1-AP(DBR1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using DBR1 antibody 16019-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human placenta using 16019-1-AP(DBR1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human placenta using 16019-1-AP(DBR1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
