Tissue expression
Cell line expression
Protein structure
PTPN18
Protein tyrosine phosphatase non-receptor type 18BDP1
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Top validated antibodies |
|||||
Proteintech Group | 17551-1-AP | 1 references | Polyclonal |
WB
EL
IHC
|
|
Novus Biologicals | H00026469-B01P | 1 references | Polyclonal |
WB
ICC |
|
antibodies-online | ABIN525721 | 1 references | Polyclonal |
WB
ICC |
|
NovoPro Bioscience Inc. | 114317 | Polyclonal |
WB
EL
IHC
|
||
Cusabio Biotech Co., Ltd | CSB-PA019030GA01HU | Polyclonal |
WB
EL
IHC
|
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider