PLN

gene product
CMD1P, PLB
The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq, Jul 2008]
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156 antibodies from 19 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Thermo Fisher Scientific Pierce
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1 antibody
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antibodies-online
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2 antibodies
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1 antibody
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2 antibodies
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2 antibodies
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1 antibody
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Sigma-Aldrich
1 antibody
Cell Signaling Technology, Inc
2 antibodies