BS8320

antibody from Bioworld Technology, Inc
Targeting: KYNU
Provider product page for BS8320
Western blot
Immunohistochemistry

Antibody data

Product number
BS8320 - Provider product page
Provider
Bioworld Technology, Inc
Product name
KYNU polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human KYNU.
Description
Kynureninase, also known as L-kynurenine hydrolase, is a 465 amino acid cytoplasmic enzyme. Kynureninase is involved in two pathways; the degredation of L-kynurenine and the biosynthesis of the cofactor NAD(+). The main function of kynureninase is to catalyze the cleavage of L-kynurenine into anthranilic acid and of L-3-hydroxykynurenine into 3-hydroxyanthranilic acid, exhibiting a preference for the L-3-hydroxy form. Kynureninase forms a homodimer, uses pyridoxal phosphate as a cofactor and is inhibited by o-methoxybenzoylalanine (OMBA). Kynureninase is widely expressed, with highest levels found in lung, placenta and liver. Deficiency in kynureninase leads to hyperkynureninuria, a disorder characterized by the inability to break down tryptophan to nicotinic acid (vitamin B6). Increased levels of kynureninase activity are observed in systemic and cerebral inflammatory conditions.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
KYNU protein structure - BS8320 shown in red.