BS7844

antibody from Bioworld Technology, Inc
Targeting: MAVS Cardif, IPS-1, KIAA1271, VISA
Provider product page for BS7844
Western blot
Immunohistochemistry

Antibody data

Product number
BS7844 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MAVS polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human MAVS.
Description
MAVS (mitochondrial antiviral-signaling protein), also known as IPS1, KIAA1271, VISA or CARDIF, is a 540 amino acid protein that contains one CARD domain and several transmembrane domains, and localizes to the outer mitochondrial membrane. Expressed throughout the body with highest ex-pression in liver, heart, placenta, skeletal muscle and peripheral blood leuk-ocytes, MAVS functions downstream of proteins, such as RIG-I, that detect double-stranded (ds) viral replication and is required for proper immune re-sponse against ds viral infection. MAVS is thought to activate pathways that lead to the induction of antiviral cytokines and may protect the cells from viral-induced apoptosis. MAVS function can be inactivated via cleavage by a protease complex that degrades the CARD and transmembrane domains, thereby preventing MAVS from interacting with other proteins. Three isoforms of MAVS are expressed due to alternative splicing events.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MAVS protein structure - BS7844 shown in red.