AP22009SU-S

antibody from Acris Antibodies GmbH

Targeting: NLRP1 CARD7, CLR17.1, DEFCAP, DKFZp586O1822, KIAA0926, NAC, NALP1, SLEV1, VAMAS1

Western blot (Supportive data in Antibodypedia)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

AP22009SU-S

Provider

Acris Antibodies GmbH

Proper citation

Acris Antibodies GmbH Cat#AP22009SU-S, RRID:AB_10778171

Product name

anti CARD7 / NLRP1 (161-180)

Antibody type

Polyclonal

Antigen

Synthetic peptide corresponding to amino acids 161-180 of human NALP1/NAC/CARD7

Reactivity

Human

Host

Rabbit

Vial size

50 µl

Western blot

Supportive validation

Submitted by

Acris Antibodies GmbH (provider)

Main image

Experimental details

Western blot analysis of NALP1 (NAC/CARD7) in adult human tissue lysates using AP22009SU-S at 1:2000. Full-length NAC protein was detected at highest levels in kidney, brain and epidermis. A smaller band was detected in thymus, possibly representing a NALP1 breakdown product or alternatively spliced form. 293T+NALP1: positive control, 293T cells transiently transfected with full-length NALP1.

Immunohistochemistry

Supportive validation

Submitted by

Acris Antibodies GmbH (provider)

Main image

Experimental details

Formalin-fixed, paraffin-embedded normal human tissue sections stained for NALP1 (CARD7/NAC) using AP22009SU-S at 1:2000. A, epidermis. B, esophagus. C, uterine cervix. D, thymus. Hematoxylin-eosin counterstain. In A-C, NALP1 expression is associated with differentiation in stratified epithelial of the skin, esophagus, and cervix.

Supportive validation

Submitted by

Acris Antibodies GmbH (provider)

Main image

Experimental details

Formalin-fixed, paraffin-embedded human tissue sections stained for NALP1 (CARD7/NAC) using AP22009SU-S at 1:2000. A, bone marrow. B, brain glioma core from a brain cancer microarray. A1 and B1 are higher magnifications of A and B, respectively. Hemaxotylin-eosin counterstain.