M00777

antibody from Boster Biological Technology
Targeting: NLRP1 CARD7, CLR17.1, DEFCAP, DKFZp586O1822, KIAA0926, NAC, NALP1, SLEV1, VAMAS1
Provider product page for M00777
Immunoprecipitation

Antibody data

Product number
M00777 - Provider product page
Provider
Boster Biological Technology
Product name
Anti-NLRP1/NALP1 Antibody (Monoclonal, Nalpy1-4)
Antibody type
Monoclonal
Description
Monoclonal, Nalpy1-4 antibody for NALP1/NLRP1 detection. Host: Mouse.Size: 100μg/vial. Tested applications: IP. Reactive species: Human. NALP1/NLRP1 information: Molecular Weight: 165866 MW; Subcellular Localization: Cytoplasm, cytosol . Cytoplasm . Inflammasome . Nucleus . Nucleocytoplasmic distribution in lymphoid organs (probably in T-cells) and in neurons. In epithelial cells, predominantly cytoplasmic; Tissue Specificity: Widely expressed (PubMed:11113115, PubMed:17164409). Abundantly expressed in primary immune cells (isoform 1 and isoform 2), including in neutrophils, monocytes/macrophages, dendritic cells (mostly Langerhans cells), and B- and T-lymphocytes (at protein level) (PubMed:15285719, PubMed:17164409). Strongly expressed in epithelial cells lining the glandular epithelium, such as that of the gastrointestinal tract (stomach, small intestine, colon), the respiratory tract (trachea and bronchi), and the endometrial and endocervical glands, gallbladder, prostate, and breast (at protein level). In testis, expressed in spermatogonia and primary spermatocytes, but not in Sertoli cells (at protein level). In the brain, expressed in neurons, in particular in pyramidal ones and in oligodendrocytes, but not detected in microglia (at protein level) (PubMed:17164409). Expressed in adult and fetal ocular tissues, including in adult and 24-week old fetal choroid, sclera, cornea, and optic nerve, as well as in adult retina and fetal retina/retinal pigment epithelium (PubMed:23349227).
Reactivity
Human
Host
Mouse
Antibody clone number
Nalpy1-4
Vial size
100μg/vial
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
NLRP1 protein structure - M00777 shown in red.