APR02275G

antibody from Leading Biology

Targeting: NLRP1 CARD7, CLR17.1, DEFCAP, DKFZp586O1822, KIAA0926, NAC, NALP1, SLEV1, VAMAS1

Western blot

Immunocytochemistry

Immunohistochemistry

Antibody data

Submit

Validation data

Product number: APR02275G - Provider product page
Provider: Leading Biology
Product name: NALP1 / NLRP1 Antibody (C-Terminus)
Antibody type: Polyclonal
Description: Able to form cytoplasmic structures termed death effector filaments. Enhances APAF1 and cytochrome c-dependent activation of pro-caspase-9 and consecutive apoptosis. Stimulates apoptosis through activation of caspase-3. Involved in activation of caspase-1 and caspase-5 as part of the NALP1 inflammasome complex which leads to processing and release of IL1B and IL18. Binds ATP.
Reactivity: Human
Host: Rabbit
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

NLRP1 protein structure - APR02275G shown in red.