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antibody from Novus Biologicals
Targeting: NLRP1
CARD7, CLR17.1, DEFCAP, DKFZp586O1822, KIAA0926, NAC, NALP1, SLEV1, VAMAS1
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [3]
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- Product number
- NBP1-54899 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-54899, RRID:AB_11010379
- Product name
- Rabbit Polyclonal NLRP1/NALP1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 ul
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references AIM2 inflammasome contributes to brain injury and chronic post-stroke cognitive impairment in mice.
Schwann cell transplantation exerts neuroprotective roles in rat model of spinal cord injury by combating inflammasome activation and improving motor recovery and remyelination.
Reduction of SIRT1 epigenetically upregulates NALP1 expression and contributes to neuropathic pain induced by chemotherapeutic drug bortezomib.
Low-level light emitting diode (LED) therapy suppresses inflammasome-mediated brain damage in experimental ischemic stroke.
NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model.
Intermittent fasting attenuates inflammasome activity in ischemic stroke.
Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke.
Inflammasome mRNA expression in human monocytes during early septic shock.
Kim H, Seo JS, Lee SY, Ha KT, Choi BT, Shin YI, Ju Yun Y, Shin HK
Brain, behavior, and immunity 2020 Jul;87:765-776
Brain, behavior, and immunity 2020 Jul;87:765-776
Schwann cell transplantation exerts neuroprotective roles in rat model of spinal cord injury by combating inflammasome activation and improving motor recovery and remyelination.
Mousavi M, Hedayatpour A, Mortezaee K, Mohamadi Y, Abolhassani F, Hassanzadeh G
Metabolic brain disease 2019 Aug;34(4):1117-1130
Metabolic brain disease 2019 Aug;34(4):1117-1130
Reduction of SIRT1 epigenetically upregulates NALP1 expression and contributes to neuropathic pain induced by chemotherapeutic drug bortezomib.
Chen K, Fan J, Luo ZF, Yang Y, Xin WJ, Liu CC
Journal of neuroinflammation 2018 Oct 20;15(1):292
Journal of neuroinflammation 2018 Oct 20;15(1):292
Low-level light emitting diode (LED) therapy suppresses inflammasome-mediated brain damage in experimental ischemic stroke.
Lee HI, Lee SW, Kim NG, Park KJ, Choi BT, Shin YI, Shin HK
Journal of biophotonics 2017 Nov;10(11):1502-1513
Journal of biophotonics 2017 Nov;10(11):1502-1513
NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model.
Tan CC, Zhang JG, Tan MS, Chen H, Meng DW, Jiang T, Meng XF, Li Y, Sun Z, Li MM, Yu JT, Tan L
Journal of neuroinflammation 2015 Jan 28;12:18
Journal of neuroinflammation 2015 Jan 28;12:18
Intermittent fasting attenuates inflammasome activity in ischemic stroke.
Fann DY, Santro T, Manzanero S, Widiapradja A, Cheng YL, Lee SY, Chunduri P, Jo DG, Stranahan AM, Mattson MP, Arumugam TV
Experimental neurology 2014 Jul;257:114-9
Experimental neurology 2014 Jul;257:114-9
Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke.
Fann DY, Lee SY, Manzanero S, Tang SC, Gelderblom M, Chunduri P, Bernreuther C, Glatzel M, Cheng YL, Thundyil J, Widiapradja A, Lok KZ, Foo SL, Wang YC, Li YI, Drummond GR, Basta M, Magnus T, Jo DG, Mattson MP, Sobey CG, Arumugam TV
Cell death & disease 2013 Sep 5;4:e790
Cell death & disease 2013 Sep 5;4:e790
Inflammasome mRNA expression in human monocytes during early septic shock.
Fahy RJ, Exline MC, Gavrilin MA, Bhatt NY, Besecker BY, Sarkar A, Hollyfield JL, Duncan MD, Nagaraja HN, Knatz NL, Hall M, Wewers MD
American journal of respiratory and critical care medicine 2008 May 1;177(9):983-8
American journal of respiratory and critical care medicine 2008 May 1;177(9):983-8
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: NLRP1/NALP1 Antibody [NBP1-54899] - NCI-H226 cell lysate, concentration 0.2-1 ug/ml.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: NLRP1/NALP1 Antibody [NBP1-54899] - Human Fetal Brain.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: NLRP1/NALP1 Antibody [NBP1-54899] - Human Fetal Brain, Antibody Dilution: 1.0 ug/ml.
