Tissue expression
Cell line expression
Protein structure
DPH5
Diphthamide biosynthesis 5CGI-30
This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Biorbyt | orb1098092 | Polyclonal |
WB
EL
ICC
FC |
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antibodies-online | ABIN4306019 | Polyclonal |
WB
ICC
IHC
|
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Cusabio Biotech Co., Ltd | CSB-PA862001LA01HU | Polyclonal |
EL
ICC
IHC
|
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Novus Biologicals | H00051611-B01P | Polyclonal |
WB
|
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Abnova Corporation | H00051611-B01P | Polyclonal |
WB
|
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