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- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Immunohistochemistry [1]
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- Product number
- MAB16451 - Provider product page
- Provider
- R&D Systems
- Product name
- Human ECE-2 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human ECE-2 in direct ELISAs and Western blots. In Western blots, 30% cross-reactivity with recombinant human (rh) ECE-1 and no cross-reactivity with rhKELL is observed.
- Reactivity
- Human
- Host
- Rat
- Conjugate
- Unconjugated
- Antigen sequence
O60344- Isotype
- IgG
- Antibody clone number
- 233914
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Endothelin-converting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta.
Palmer JC, Baig S, Kehoe PG, Love S
The American journal of pathology 2009 Jul;175(1):262-70
The American journal of pathology 2009 Jul;175(1):262-70
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Supportive validation
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- R&D Systems (provider)
- Main image
- Experimental details
- ECE-2 in Human Brain. ECE-2 was detected in immersion fixed paraffin-embedded sections of human brain (cortex) using 3 µg/mL Rat Anti-Human ECE-2 Monoclonal Antibody (Catalog # MAB16451) overnight at 4 °C. Tissue was stained with the Anti-Rat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS017) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
