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Learn10-7569-25
antibody from ABEOMICS Inc.
Targeting: PAPPA
ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- 10-7569-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-PAPP-A Antibody
- Antibody type
- Monoclonal
- Description
- PAPP-A (pregnancy-associated plasma protein A) is a zinc metalloproteinase in the insulin-like growth factor system that is expressed by tissues outside of pregnancy and involved in normal and dysregulated growth. It has prognostic impact in pregnancy and acute coronary syndrome. PAPP-A regulate the activity of insulin-like growth factor (IGF) signal pathway through proteolytic degradation of IGF binding proteins (IGFBPs) thereby increasing the local concentration of free IGFs available to receptors. PAPP-A levels is associated with abnormal glucose metabolism and increased risk of atherosclerosis in AGHD (Adult Growth Hormone Deficiency) patients.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
A partial length recombinant PAPP-A
protein (amino acids 332-561) was
used as the immunogen for this anti
body.- Isotype
- IgG
- Antibody clone number
- ABM4C62
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of PAPP-A in human Placenta tissue using PAPP-A antibody (Clone: ABM4C62) at 5 µg/ml.
- Protocol
- Protocol
