Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 12080-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- VTCN1 antibody
- Antibody type
- Polyclonal
- Description
- VTCN1 antibody (Cat. #12080-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Interferon-γ in the tumor microenvironment promotes the expression of B7H4 in colorectal cancer cells, thereby inhibiting cytotoxic T cells.
The deubiquitinase USP2a promotes tumor immunosuppression by stabilizing immune checkpoint B7-H4 in lung adenocarcinoma harboring EGFR-activating mutants.
A Novel Gene Pair CSTF2/DPE2A Impacts Prognosis and Cell Cycle of Hepatocellular Carcinoma.
Dysregulated B7H4/JAK2/STAT3 Pathway Involves in Hypertriglyceridemia Acute Pancreatitis and Is Attenuated by Baicalin.
B7-H4 is increased in lung adenocarcinoma harboring EGFR-activating mutations and contributes to immunosuppression.
Alpha-Fetoprotein Regulates the Expression of Immune-Related Proteins through the NF-κB (P65) Pathway in Hepatocellular Carcinoma Cells.
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Insulin-like growth factor-1 receptor induces immunosuppression in lung cancer by upregulating B7-H4 expression through the MEK/ERK signaling pathway.
RNA-Seq Analysis of Differentiated Keratinocytes Reveals a Massive Response to Late Events during Human Papillomavirus 16 Infection, Including Loss of Epithelial Barrier Function.
Jing ZL, Liu GL, Zhou N, Xu DY, Feng N, Lei Y, Ma LL, Tang MS, Tong GH, Tang N, Deng YJ
Scientific reports 2024 Mar 13;14(1):6053
Scientific reports 2024 Mar 13;14(1):6053
The deubiquitinase USP2a promotes tumor immunosuppression by stabilizing immune checkpoint B7-H4 in lung adenocarcinoma harboring EGFR-activating mutants.
Lu Y, Sun Y, Zhang J, Kong M, Zhao Z, Sun B, Wang Y, Jiang Y, Chen S, Wang C, Tong Y, Wen L, Huang M, Wu F, Zhang L
Cancer letters 2024 Aug 1;596:217020
Cancer letters 2024 Aug 1;596:217020
A Novel Gene Pair CSTF2/DPE2A Impacts Prognosis and Cell Cycle of Hepatocellular Carcinoma.
Huang Y, Xu J, Xie C, Liao Y, Lin R, Zeng Y, Yu F
Journal of hepatocellular carcinoma 2023;10:1639-1657
Journal of hepatocellular carcinoma 2023;10:1639-1657
Dysregulated B7H4/JAK2/STAT3 Pathway Involves in Hypertriglyceridemia Acute Pancreatitis and Is Attenuated by Baicalin.
Yang J, Han F, Wu G, Dong Y, Su H, Xu J, Li J
Digestive diseases and sciences 2023 Feb;68(2):478-486
Digestive diseases and sciences 2023 Feb;68(2):478-486
B7-H4 is increased in lung adenocarcinoma harboring EGFR-activating mutations and contributes to immunosuppression.
Lu Y, Wu F, Cao Q, Sun Y, Huang M, Xiao J, Zhou B, Zhang L
Oncogene 2022 Jan;41(5):704-717
Oncogene 2022 Jan;41(5):704-717
Alpha-Fetoprotein Regulates the Expression of Immune-Related Proteins through the NF-κB (P65) Pathway in Hepatocellular Carcinoma Cells.
Li QT, Qiu MJ, Yang SL, Fang X, He XX, Wang MM, Li YN, Xiong ZF, Huang S
Journal of oncology 2020;2020:9327512
Journal of oncology 2020;2020:9327512
Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8.
Li A, Zhang N, Zhao Z, Chen Y, Zhang L
Oncology letters 2020 Aug;20(2):1535-1544
Oncology letters 2020 Aug;20(2):1535-1544
Insulin-like growth factor-1 receptor induces immunosuppression in lung cancer by upregulating B7-H4 expression through the MEK/ERK signaling pathway.
Zhao Z, Zhang N, Li A, Zhou B, Chen Y, Chen S, Huang M, Wu F, Zhang L
Cancer letters 2020 Aug 10;485:14-26
Cancer letters 2020 Aug 10;485:14-26
RNA-Seq Analysis of Differentiated Keratinocytes Reveals a Massive Response to Late Events during Human Papillomavirus 16 Infection, Including Loss of Epithelial Barrier Function.
Klymenko T, Gu Q, Herbert I, Stevenson A, Iliev V, Watkins G, Pollock C, Bhatia R, Cuschieri K, Herzyk P, Gatherer D, Graham SV
Journal of virology 2017 Dec 15;91(24)
Journal of virology 2017 Dec 15;91(24)
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The VTCN1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human VTCN1. This antibody recognizes human,mouse,rat antigen. The VTCN1 antibody has been validated for the following applications: ELISA, WB analysis.