MAB2698

antibody from Abnova Corporation

Targeting: JAK1 JAK1A, JAK1B, JTK3

Western blot (Data presented on provider website)

ELISA (Recommended by provider)

Antibody Data

Product number

MAB2698

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#MAB2698, RRID:AB_10632074

Product name

JAK1 monoclonal antibody, clone AF28B1

Antibody type

Monoclonal

Antigen

Recombinant His fusion protein corresponding to human JAK1.

Description

Mouse monoclonal antibody raised against recombinant JAK1.

Reactivity

Human, Rat

Host

Mouse

Vial size

100 μL

Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Dual role of the Jak1 FERM and kinase domains in cytokine receptor binding and in stimulation-dependent Jak activation.

Haan S, Margue C, Engrand A, Rolvering C, Schmitz-Van de Leur H, Heinrich PC, Behrmann I, Haan C
Journal of immunology (Baltimore, Md. : 1950) 2008 Jan 15;180(2):998-1007

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Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity.

Cheng H, Ross JA, Frost JA, Kirken RA
Molecular and cellular biology 2008 Apr;28(7):2271-82

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Series introduction. JAK-STAT signaling in human disease.

Schindler CW
The Journal of clinical investigation 2002 May;109(9):1133-7