Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 15704-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15704-1-AP, RRID:AB_2261979
- Product name
- EIF4G1 antibody
- Antibody type
- Polyclonal
- Description
- EIF4G1 antibody (Cat. #15704-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ADAR1 limits stress granule formation through both translation-dependent and translation-independent mechanisms.
The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation.
RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.
Inhibition of Antiviral Innate Immunity by Foot-and-Mouth Disease Virus Lpro through Interaction with the N-Terminal Domain of Swine RNase L.
Translational Factor eIF4G1 Regulates Glucose Homeostasis and Pancreatic β-Cell Function.
ALS-Linked Mutant SOD1 Associates with TIA-1 and Alters Stress Granule Dynamics.
EIF4G1 is a novel candidate gene associated with severe asthenozoospermia.
Cellular cap-binding protein, eIF4E, promotes picornavirus genome restructuring and translation.
Construction of a subgenomic CV-B3 replicon expressing emerald green fluorescent protein to assess viral replication of a cardiotropic enterovirus strain in cultured human cells.
SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation.
Protease 2A induces stress granule formation during coxsackievirus B3 and enterovirus 71 infections.
Corbet GA, Burke JM, Parker R
Journal of cell science 2021 Sep 1;134(17)
Journal of cell science 2021 Sep 1;134(17)
The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation.
Sun L, Wang W, Han C, Huang W, Sun Y, Fang K, Zeng Z, Yang Q, Pan Q, Chen T, Luo X, Chen Y
Molecular cell 2021 Nov 4;81(21):4493-4508.e9
Molecular cell 2021 Nov 4;81(21):4493-4508.e9
RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site.
George J, Li Y, Kadamberi IP, Parashar D, Tsaih SW, Gupta P, Geethadevi A, Chen C, Ghosh C, Sun Y, Mittal S, Ramchandran R, Rui H, Lopez-Berestein G, Rodriguez-Aguayo C, Leone G, Rader JS, Sood AK, Dey M, Pradeep S, Chaluvally-Raghavan P
Cell reports 2021 Nov 2;37(5):109934
Cell reports 2021 Nov 2;37(5):109934
Inhibition of Antiviral Innate Immunity by Foot-and-Mouth Disease Virus Lpro through Interaction with the N-Terminal Domain of Swine RNase L.
Sui C, Jiang D, Wu X, Liu S, Li F, Pan L, Cong X, Li J, Yoo D, Rock DL, Miller LC, Lee C, Du Y, Qi J
Journal of virology 2021 Jul 12;95(15):e0036121
Journal of virology 2021 Jul 12;95(15):e0036121
Translational Factor eIF4G1 Regulates Glucose Homeostasis and Pancreatic β-Cell Function.
Jo S, Lockridge A, Mohan R, Esch N, Schlichting R, Panigrahy N, Essawy A, Gustafson E, Alejandro EU
Diabetes 2021 Jan;70(1):155-170
Diabetes 2021 Jan;70(1):155-170
ALS-Linked Mutant SOD1 Associates with TIA-1 and Alters Stress Granule Dynamics.
Lee DY, Jeon GS, Sung JJ
Neurochemical research 2020 Dec;45(12):2884-2893
Neurochemical research 2020 Dec;45(12):2884-2893
EIF4G1 is a novel candidate gene associated with severe asthenozoospermia.
Sha Y, Liu W, Huang X, Li Y, Ji Z, Mei L, Lin S, Kong S, Lu J, Kong L, Zhu X, Lu Z, Ding L
Molecular genetics & genomic medicine 2019 Aug;7(8):e807
Molecular genetics & genomic medicine 2019 Aug;7(8):e807
Cellular cap-binding protein, eIF4E, promotes picornavirus genome restructuring and translation.
Avanzino BC, Fuchs G, Fraser CS
Proceedings of the National Academy of Sciences of the United States of America 2017 Sep 5;114(36):9611-9616
Proceedings of the National Academy of Sciences of the United States of America 2017 Sep 5;114(36):9611-9616
Construction of a subgenomic CV-B3 replicon expressing emerald green fluorescent protein to assess viral replication of a cardiotropic enterovirus strain in cultured human cells.
Wehbe M, Huguenin A, Leveque N, Semler BL, Hamze M, Andreoletti L, Bouin A
Journal of virological methods 2016 Apr;230:1-8
Journal of virological methods 2016 Apr;230:1-8
SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation.
Hu S, Li J, Xu F, Mei S, Le Duff Y, Yin L, Pang X, Cen S, Jin Q, Liang C, Guo F
PLoS genetics 2015 Jul;11(7):e1005367
PLoS genetics 2015 Jul;11(7):e1005367
Protease 2A induces stress granule formation during coxsackievirus B3 and enterovirus 71 infections.
Wu S, Wang Y, Lin L, Si X, Wang T, Zhong X, Tong L, Luan Y, Chen Y, Li X, Zhang F, Zhao W, Zhong Z
Virology journal 2014 Nov 20;11:192
Virology journal 2014 Nov 20;11:192
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 15704-1-AP(EIF4G1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using EIF4G1 antibody 15704-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 15704-1-AP(EIF4G1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 15704-1-AP(EIF4G1 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue