Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [44]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11097-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11097-1-AP, RRID:AB_2286705
- Product name
- SRC antibody
- Antibody type
- Polyclonal
- Description
- SRC antibody (Cat. #11097-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, hamster and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Hamster
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references lncRNA Gm16410 Mediates PM2.5-Induced Macrophage Activation via PI3K/AKT Pathway.
The Synaptic Vesicle Protein 2A Interacts With Key Pathogenic Factors in Alzheimer's Disease: Implications for Treatment.
Inhibition of Phosphodiesterase 5 Promotes the Aromatase-Mediated Estrogen Biosynthesis in Osteoblastic Cells by Activation of cGMP/PKG/SHP2 Pathway.
Identification of a Novel Ferroptosis-Related Gene Prognostic Signature in Bladder Cancer.
A network pharmacology strategy to investigate the anti-osteoarthritis mechanism of main lignans components of Schisandrae Fructus.
Silencing ZIC2 abrogates tumorigenesis and anoikis resistance of non-small cell lung cancer cells by inhibiting Src/FAK signaling.
TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.
Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway.
A network-based analysis and experimental validation of traditional Chinese medicine Yuanhu Zhitong Formula in treating neuropathic pain.
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
Protein tyrosine phosphatase 1B(PTP1B) promotes melanoma cells progression through Src activation.
Qihuzha granule attenuated LPS-induced acute spleen injury in mice via Src/MAPK/Stat3 signal pathway.
Strategies to Attenuate Myocardial Infarction and No-Reflow Through Preservation of Vascular Integrity by Pigment Epithelium-Derived Factor.
Quantitative proteomics revealed modulation of macrophages by MetQ gene of Streptococcus suis serotype 2.
Downregulation of the ubiquitin ligase KBTBD8 prevented epithelial ovarian cancer progression.
Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes.
The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein.
Targeting LRIG2 overcomes resistance to EGFR inhibitor in glioblastoma by modulating GAS6/AXL/SRC signaling.
A non-canonical rhodopsin-mediated insulin receptor signaling pathway in retinal photoreceptor neurons.
SEMA3C Promotes Cervical Cancer Growth and Is Associated With Poor Prognosis.
Antimetastatic Effect of Fucoidan-Sargassum against Liver Cancer Cell Invadopodia Formation via Targeting Integrin αVβ3 and Mediating αVβ3/Src/E2F1 Signaling.
TRIM50 acts as a novel Src suppressor and inhibits ovarian cancer progression.
Ginkgolic Acids Impair Mitochondrial Function by Decreasing Mitochondrial Biogenesis and Promoting FUNDC1-Dependent Mitophagy.
DR region specific antibody ameliorated but ouabain worsened renal injury in nephrectomized rats through regulating Na,K-ATPase mediated signaling pathways.
NLRP3 regulates platelet integrin αIIbβ3 outside-in signaling, hemostasis and arterial thrombosis.
Hypoxia-Inducible Factor-1α (HIF-1α) Expression on Endothelial Cells in Juvenile Nasopharyngeal Angiofibroma: A Review of 70 cases and Tissue Microarray Analysis.
DRm217 attenuates myocardial ischemia-reperfusion injury via stabilizing plasma membrane Na+-K+-ATPase, inhibiting Na+-K+-ATPase/ROS pathway and activating PI3K/Akt and ERK1/2.
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
ANXA2 promotes esophageal cancer progression by activating MYC-HIF1A-VEGF axis.
Histochemical evidence of IGF2 mRNA-binding protein 2-mediated regulation of osteoclast function and adhesive ability.
Dioscin Inhibits HSC-T6 Cell Migration via Adjusting SDC-4 Expression: Insights from iTRAQ-Based Quantitative Proteomics.
PALLD Regulates Phagocytosis by Enabling Timely Actin Polymerization and Depolymerization.
Regulation of Na+-K+-ATPase effected high glucose-induced myocardial cell injury through c-Src dependent NADPH oxidase/ROS pathway.
Activation of Na+-K+-ATPase with DRm217 attenuates oxidative stress-induced myocardial cell injury via closing Na+-K+-ATPase/Src/Ros amplifier.
Extracellular matrix protein ITGBL1 promotes ovarian cancer cell migration and adhesion through Wnt/PCP signaling and FAK/SRC pathway.
Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation.
Gefitinib enhances oxaliplatin-induced apoptosis mediated by Src and PKC-modulated gap junction function.
Paper-based microreactor array for rapid screening of cell signaling cascades.
Metalloproteinase MT1-MMP islets act as memory devices for podosome reemergence.
Mechanisms of growth-promoting and tumor-protecting effects of epithelial nicotinic acetylcholine receptors.
Histochemical evidence of zoledronate inhibiting c-src expression and interfering with CD44/OPN-mediated osteoclast adhesion in the tibiae of mice.
EphB2 contributes to human naive B-cell activation and is regulated by miR-185.
Microarray analyses reveal liver metastasis-related genes in metastatic colorectal cancer cell model.
Phosphorylated Syk expression is enhanced in Nasu-Hakola disease brains.
Xu J, Xu H, Ma K, Wang Y, Niu B, Zhang L, Li F
Frontiers in cell and developmental biology 2021;9:618045
Frontiers in cell and developmental biology 2021;9:618045
The Synaptic Vesicle Protein 2A Interacts With Key Pathogenic Factors in Alzheimer's Disease: Implications for Treatment.
Kong Y, Huang L, Li W, Liu X, Zhou Y, Liu C, Zhang S, Xie F, Zhang Z, Jiang D, Zhou W, Ni R, Zhang C, Sun B, Wang J, Guan Y
Frontiers in cell and developmental biology 2021;9:609908
Frontiers in cell and developmental biology 2021;9:609908
Inhibition of Phosphodiesterase 5 Promotes the Aromatase-Mediated Estrogen Biosynthesis in Osteoblastic Cells by Activation of cGMP/PKG/SHP2 Pathway.
Wisanwattana W, Wongkrajang K, Cao DY, Shi XK, Zhang ZH, Zhou ZY, Li F, Mei QG, Wang C, Suksamrarn A, Zhang GL, Wang F
Frontiers in endocrinology 2021;12:636784
Frontiers in endocrinology 2021;12:636784
Identification of a Novel Ferroptosis-Related Gene Prognostic Signature in Bladder Cancer.
Sun J, Yue W, You J, Wei X, Huang Y, Ling Z, Hou J
Frontiers in oncology 2021;11:730716
Frontiers in oncology 2021;11:730716
A network pharmacology strategy to investigate the anti-osteoarthritis mechanism of main lignans components of Schisandrae Fructus.
Min L, Wu Y, Cao G, Mi D, Chen C
International immunopharmacology 2021 Sep;98:107873
International immunopharmacology 2021 Sep;98:107873
Silencing ZIC2 abrogates tumorigenesis and anoikis resistance of non-small cell lung cancer cells by inhibiting Src/FAK signaling.
Liu A, Xie H, Li R, Ren L, Yang B, Dai L, Lu W, Liu B, Ren D, Zhang X, Chen Q, Huang Y, Shi K
Molecular therapy oncolytics 2021 Sep 24;22:195-208
Molecular therapy oncolytics 2021 Sep 24;22:195-208
TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.
Wu J, Wang Y, Yang Y, Liu F, Chen J, Jiang Z, Jiang Z
Aging 2021 Sep 13;13(17):21571-21586
Aging 2021 Sep 13;13(17):21571-21586
Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway.
Liu CD, Liu NN, Zhang S, Ma GD, Yang HG, Kong LL, Du GH
Acta pharmacologica Sinica 2021 Mar;42(3):370-381
Acta pharmacologica Sinica 2021 Mar;42(3):370-381
A network-based analysis and experimental validation of traditional Chinese medicine Yuanhu Zhitong Formula in treating neuropathic pain.
Liu T, Li T, Chen X, Zhang K, Li M, Yao W, Zhang C, Wan L
Journal of ethnopharmacology 2021 Jun 28;274:114037
Journal of ethnopharmacology 2021 Jun 28;274:114037
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
Lu YZ, Liang LM, Cheng PP, Xiong L, Wang M, Song LJ, Yu F, He XL, Xiong L, Wang XR, Xin JB, Ye H, Ma WL
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
Protein tyrosine phosphatase 1B(PTP1B) promotes melanoma cells progression through Src activation.
Wang Q, Pan Y, Zhao L, Qi F, Liu J
Bioengineered 2021 Dec;12(1):8396-8406
Bioengineered 2021 Dec;12(1):8396-8406
Qihuzha granule attenuated LPS-induced acute spleen injury in mice via Src/MAPK/Stat3 signal pathway.
Zhong T, Feng M, Su M, Wang D, Li Q, Jia S, Luo F, Wang H, Hu E, Yang X, Fan Y
Journal of ethnopharmacology 2021 Dec 5;281:114458
Journal of ethnopharmacology 2021 Dec 5;281:114458
Strategies to Attenuate Myocardial Infarction and No-Reflow Through Preservation of Vascular Integrity by Pigment Epithelium-Derived Factor.
Zhang H, Li Z, Quan X, Liu X, Sun T, Wei T, Pan J, Liu Z, Wang M, Dong H, Zhang Z
Human gene therapy 2021 Aug 27;
Human gene therapy 2021 Aug 27;
Quantitative proteomics revealed modulation of macrophages by MetQ gene of Streptococcus suis serotype 2.
Pei X, Liu J, Liu M, Zhou H, Wang X, Fan H
AMB Express 2020 Oct 30;10(1):195
AMB Express 2020 Oct 30;10(1):195
Downregulation of the ubiquitin ligase KBTBD8 prevented epithelial ovarian cancer progression.
Du L, Li CR, He QF, Li XH, Yang LF, Zou Y, Yang ZX, Zhang D, Xing XW
Molecular medicine (Cambridge, Mass.) 2020 Oct 27;26(1):96
Molecular medicine (Cambridge, Mass.) 2020 Oct 27;26(1):96
Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes.
Han P, Hanlon D, Arshad N, Lee JS, Tatsuno K, Robinson E, Filler R, Sobolev O, Cote C, Rivera-Molina F, Toomre D, Fahmy T, Edelson R
Science advances 2020 Mar;6(11):eaaz1580
Science advances 2020 Mar;6(11):eaaz1580
The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein.
Zhu L, Qin C, Li T, Ma X, Qiu Y, Lin Y, Ma D, Qin Z, Sun C, Shen X, Zhao Y, Han L
Cell death and differentiation 2020 Jun;27(6):1819-1831
Cell death and differentiation 2020 Jun;27(6):1819-1831
Targeting LRIG2 overcomes resistance to EGFR inhibitor in glioblastoma by modulating GAS6/AXL/SRC signaling.
Dong M, Xiao Q, Hu J, Cheng F, Zhang P, Zong W, Tang Q, Li X, Mao F, He Y, Yu X, Wan F, Lei T, Guo D, Wang B
Cancer gene therapy 2020 Dec;27(12):878-897
Cancer gene therapy 2020 Dec;27(12):878-897
A non-canonical rhodopsin-mediated insulin receptor signaling pathway in retinal photoreceptor neurons.
Rajala A, Rajala RVS
Cell biology international 2020 Apr;44(4):1020-1027
Cell biology international 2020 Apr;44(4):1020-1027
SEMA3C Promotes Cervical Cancer Growth and Is Associated With Poor Prognosis.
Liu R, Shuai Y, Luo J, Zhang Z
Frontiers in oncology 2019;9:1035
Frontiers in oncology 2019;9:1035
Antimetastatic Effect of Fucoidan-Sargassum against Liver Cancer Cell Invadopodia Formation via Targeting Integrin αVβ3 and Mediating αVβ3/Src/E2F1 Signaling.
Pan TJ, Li LX, Zhang JW, Yang ZS, Shi DM, Yang YK, Wu WZ
Journal of Cancer 2019;10(20):4777-4792
Journal of Cancer 2019;10(20):4777-4792
TRIM50 acts as a novel Src suppressor and inhibits ovarian cancer progression.
Qiu Y, Liu P, Ma X, Ma X, Zhu L, Lin Y, You Y, Yu W, Ma D, Sun C, Qin Z, Zhao Y, Shi J, Han L
Biochimica et biophysica acta. Molecular cell research 2019 Sep;1866(9):1412-1420
Biochimica et biophysica acta. Molecular cell research 2019 Sep;1866(9):1412-1420
Ginkgolic Acids Impair Mitochondrial Function by Decreasing Mitochondrial Biogenesis and Promoting FUNDC1-Dependent Mitophagy.
Wang W, Wang M, Ruan Y, Tan J, Wang H, Yang T, Li J, Zhou Q
Journal of agricultural and food chemistry 2019 Sep 11;67(36):10097-10106
Journal of agricultural and food chemistry 2019 Sep 11;67(36):10097-10106
DR region specific antibody ameliorated but ouabain worsened renal injury in nephrectomized rats through regulating Na,K-ATPase mediated signaling pathways.
Wang J, Ullah SH, Li M, Zhang M, Zhang F, Zheng J, Yan X
Aging 2019 Feb 26;11(4):1151-1162
Aging 2019 Feb 26;11(4):1151-1162
NLRP3 regulates platelet integrin αIIbβ3 outside-in signaling, hemostasis and arterial thrombosis.
Qiao J, Wu X, Luo Q, Wei G, Xu M, Wu Y, Liu Y, Li X, Zi J, Ju W, Fu L, Chen C, Wu Q, Zhu S, Qi K, Li D, Li Z, Andrews RK, Zeng L, Gardiner EE, Xu K
Haematologica 2018 Sep;103(9):1568-1576
Haematologica 2018 Sep;103(9):1568-1576
Hypoxia-Inducible Factor-1α (HIF-1α) Expression on Endothelial Cells in Juvenile Nasopharyngeal Angiofibroma: A Review of 70 cases and Tissue Microarray Analysis.
Song X, Yang C, Zhang H, Wang J, Sun X, Hu L, Liu Z, Wang D
The Annals of otology, rhinology, and laryngology 2018 Jun;127(6):357-366
The Annals of otology, rhinology, and laryngology 2018 Jun;127(6):357-366
DRm217 attenuates myocardial ischemia-reperfusion injury via stabilizing plasma membrane Na+-K+-ATPase, inhibiting Na+-K+-ATPase/ROS pathway and activating PI3K/Akt and ERK1/2.
Yan X, Xun M, Wu L, Du X, Zhang F, Zheng J
Toxicology and applied pharmacology 2018 Jun 15;349:62-71
Toxicology and applied pharmacology 2018 Jun 15;349:62-71
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
Cheng Z, Liu L, Wang Z, Cai Y, Xu Q, Chen P
International journal of molecular sciences 2018 Feb 15;19(2)
International journal of molecular sciences 2018 Feb 15;19(2)
ANXA2 promotes esophageal cancer progression by activating MYC-HIF1A-VEGF axis.
Ma S, Lu CC, Yang LY, Wang JJ, Wang BS, Cai HQ, Hao JJ, Xu X, Cai Y, Zhang Y, Wang MR
Journal of experimental & clinical cancer research : CR 2018 Aug 6;37(1):183
Journal of experimental & clinical cancer research : CR 2018 Aug 6;37(1):183
Histochemical evidence of IGF2 mRNA-binding protein 2-mediated regulation of osteoclast function and adhesive ability.
Liu H, Li D, Liu S, Liu Z, Li M
Histochemistry and cell biology 2018 Apr;149(4):343-351
Histochemistry and cell biology 2018 Apr;149(4):343-351
Dioscin Inhibits HSC-T6 Cell Migration via Adjusting SDC-4 Expression: Insights from iTRAQ-Based Quantitative Proteomics.
Yin L, Qi Y, Xu Y, Xu L, Han X, Tao X, Song S, Peng J
Frontiers in pharmacology 2017;8:665
Frontiers in pharmacology 2017;8:665
PALLD Regulates Phagocytosis by Enabling Timely Actin Polymerization and Depolymerization.
Sun HM, Chen XL, Chen XJ, Liu J, Ma L, Wu HY, Huang QH, Xi XD, Yin T, Zhu J, Chen Z, Chen SJ
Journal of immunology (Baltimore, Md. : 1950) 2017 Sep 1;199(5):1817-1826
Journal of immunology (Baltimore, Md. : 1950) 2017 Sep 1;199(5):1817-1826
Regulation of Na+-K+-ATPase effected high glucose-induced myocardial cell injury through c-Src dependent NADPH oxidase/ROS pathway.
Yan X, Xun M, Dou X, Wu L, Han Y, Zheng J
Experimental cell research 2017 Aug 15;357(2):243-251
Experimental cell research 2017 Aug 15;357(2):243-251
Activation of Na+-K+-ATPase with DRm217 attenuates oxidative stress-induced myocardial cell injury via closing Na+-K+-ATPase/Src/Ros amplifier.
Yan X, Xun M, Dou X, Wu L, Zhang F, Zheng J
Apoptosis : an international journal on programmed cell death 2017 Apr;22(4):531-543
Apoptosis : an international journal on programmed cell death 2017 Apr;22(4):531-543
Extracellular matrix protein ITGBL1 promotes ovarian cancer cell migration and adhesion through Wnt/PCP signaling and FAK/SRC pathway.
Sun L, Wang D, Li X, Zhang L, Zhang H, Zhang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Jul;81:145-151
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Jul;81:145-151
Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation.
Zheng J, Huang X, Tan W, Yu D, Du Z, Chang J, Wei L, Han Y, Wang C, Che X, Zhou Y, Miao X, Jiang G, Yu X, Yang X, Cao G, Zuo C, Li Z, Wang C, Cheung ST, Jia Y, Zheng X, Shen H, Wu C, Lin D
Nature genetics 2016 Jul;48(7):747-57
Nature genetics 2016 Jul;48(7):747-57
Gefitinib enhances oxaliplatin-induced apoptosis mediated by Src and PKC-modulated gap junction function.
Wu JF, Ji J, Dong SY, Li BB, Yu ML, Wu DD, Tao L, Tong XH
Oncology reports 2016 Dec;36(6):3251-3258
Oncology reports 2016 Dec;36(6):3251-3258
Paper-based microreactor array for rapid screening of cell signaling cascades.
Huang CH, Lei KF, Tsang NM
Lab on a chip 2016 Aug 7;16(15):2911-20
Lab on a chip 2016 Aug 7;16(15):2911-20
Metalloproteinase MT1-MMP islets act as memory devices for podosome reemergence.
El Azzouzi K, Wiesner C, Linder S
The Journal of cell biology 2016 Apr 11;213(1):109-25
The Journal of cell biology 2016 Apr 11;213(1):109-25
Mechanisms of growth-promoting and tumor-protecting effects of epithelial nicotinic acetylcholine receptors.
Chernyavsky AI, Shchepotin IB, Grando SA
International immunopharmacology 2015 Nov;29(1):36-44
International immunopharmacology 2015 Nov;29(1):36-44
Histochemical evidence of zoledronate inhibiting c-src expression and interfering with CD44/OPN-mediated osteoclast adhesion in the tibiae of mice.
Liu H, Cui J, Sun J, Du J, Feng W, Sun B, Li J, Han X, Liu B, Yimin, Oda K, Amizuka N, Li M
Journal of molecular histology 2015 Jun;46(3):313-23
Journal of molecular histology 2015 Jun;46(3):313-23
EphB2 contributes to human naive B-cell activation and is regulated by miR-185.
Yu M, Liang W, Wen S, Zhao T, Zhu MX, Li HH, Long Q, Wang M, Cheng X, Liao YH, Yuan J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014 Aug;28(8):3609-17
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014 Aug;28(8):3609-17
Microarray analyses reveal liver metastasis-related genes in metastatic colorectal cancer cell model.
Chen Q, Chen L, Zhao R, Yang XD, Imran K, Xing CG
Journal of cancer research and clinical oncology 2013 Jul;139(7):1169-78
Journal of cancer research and clinical oncology 2013 Jul;139(7):1169-78
Phosphorylated Syk expression is enhanced in Nasu-Hakola disease brains.
Satoh J, Tabunoki H, Ishida T, Yagishita S, Jinnai K, Futamura N, Kobayashi M, Toyoshima I, Yoshioka T, Enomoto K, Arai N, Saito Y, Arima K
Neuropathology : official journal of the Japanese Society of Neuropathology 2012 Apr;32(2):149-57
Neuropathology : official journal of the Japanese Society of Neuropathology 2012 Apr;32(2):149-57
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A431 cells were subjected to SDS PAGE followed by western blot with 11097-1-AP(SRC antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-SRC (IP:11097-1-AP, 5ug; Detection:11097-1-AP 1:1000) with SH-SY5Y cells lysate 2900ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 11097-1-AP(SRC antibody) at dilution of 1:10 (under 10x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SRC antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SRC. This antibody recognizes human, mouse, rat, hamster antigen. The SRC antibody has been validated for the following applications: ELISA, WB, IHC, IP, FC analysis.
