UBE2Q1

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart. [provided by RefSeq, Jul 2008]

Description

Ubiquitin conjugating enzyme E2 Q1

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Centrosome, Cytosol

Predicted location

Intracellular

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

1 (154548577 - 154559028)

Ensembl ID

ENSG00000160714  (ver. 103.38)

Orthologs

Mouse Ube2q1: ENSMUSG00000042572

UniProt

Q7Z7E8

neXtProt

NX_Q7Z7E8

Human splice variants
Mouse splice variants

Protein structure