BS7831

antibody from Bioworld Technology, Inc
Targeting: FDPS
Provider product page for BS7831
Western blot
Immunohistochemistry

Antibody data

Product number
BS7831 - Provider product page
Provider
Bioworld Technology, Inc
Product name
FDPS polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human FDPS.
Description
FDPS (farnesyl diphosphate synthase), also known as FPS or FPPS, is a 419 amino acid enzyme belonging to the FPP/GGPP synthetase family. Localized to cytoplasm and peroxisome, FDPS expression is regulated by phorbol esters and polyunsaturated fatty acids. FDPS assists in cholesterol biosynthesis, post-translational protein modifications and synthesis of steroid hormones in the isoprenoid pathway.FDPS catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FDPS is inactivated by interferon-induced RSAD2, which may result in the disruption of lipid rafts at the plasma membrane. Existing as a homodimer, FDPS may have anti-viral effects when inactivated by RSAD2. Reduced activity of FDPS in liver may partly be the cause of Zellweger syndrome and neonatal adrenoleukodystrophy, both of which are known to be peroxisomal deficiency diseases.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
FDPS protein structure - BS7831 shown in red.