FNab03065

antibody from FineTest Biotech
Targeting: FDPS
Provider product page for FNab03065
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
FNab03065 - Provider product page
Provider
FineTest Biotech
Product name
FDPS antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
farnesyl diphosphate synthase (farn
esyl pyrophosphate synthetase, dime
thylallyltranstransferase, geranylt
ranstransferase)
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
FDPS protein structure - FNab03065 shown in red.