9559

antibody from Cell Signaling Technology, Inc

Targeting: PTEN BZS, MHAM, MMAC1, PTEN1, TEP1

Western blot (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

9559

Provider

Cell Signaling Technology, Inc

Proper citation

Cell Signaling Technology Cat#9559, RRID:AB_390810

Product name

PTEN (138G6) Rabbit mAb

Antibody type

Monoclonal

Reactivity

Human, Mouse, Rat, Simian

Host

Rabbit

Storage

-20°C

References

Submitted references

Loss of phosphatase and tensin homolog protein expression is an independent poor prognostic marker in lung adenocarcinoma.

Yanagawa N, Leduc C, Kohler D, Saieg MA, John T, Sykes J, Yoshimoto M, Pintilie M, Squire J, Shepherd FA, Tsao MS
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2012 Oct;7(10):1513-21

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A robust immunohistochemical assay for detecting PTEN expression in human tumors.

Sangale Z, Prass C, Carlson A, Tikishvili E, Degrado J, Lanchbury J, Stone S
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2011 Mar;19(2):173-83

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Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma.

Pitter KL, Galbán CJ, Galbán S, Tehrani OS, Li F, Charles N, Bradbury MS, Becher OJ, Chenevert TL, Rehemtulla A, Ross BD, Holland EC, Hambardzumyan D
PloS one 2011 Jan 18;6(1):e14545

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XIAP gene expression and function is regulated by autocrine and paracrine TGF-beta signaling.

Van Themsche C, Chaudhry P, Leblanc V, Parent S, Asselin E
Molecular cancer 2010 Aug 16;9:216

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Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation.

Poliseno L, Salmena L, Riccardi L, Fornari A, Song MS, Hobbs RM, Sportoletti P, Varmeh S, Egia A, Fedele G, Rameh L, Loda M, Pandolfi PP
Science signaling 2010 Apr 13;3(117):ra29

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mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.

Guertin DA, Stevens DM, Saitoh M, Kinkel S, Crosby K, Sheen JH, Mullholland DJ, Magnuson MA, Wu H, Sabatini DM
Cancer cell 2009 Feb 3;15(2):148-59

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Synergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression.

Laguë MN, Paquet M, Fan HY, Kaartinen MJ, Chu S, Jamin SP, Behringer RR, Fuller PJ, Mitchell A, Doré M, Huneault LM, Richards JS, Boerboom D
Carcinogenesis 2008 Nov;29(11):2062-72

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Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.

Saal LH, Gruvberger-Saal SK, Persson C, Lövgren K, Jumppanen M, Staaf J, Jönsson G, Pires MM, Maurer M, Holm K, Koujak S, Subramaniyam S, Vallon-Christersson J, Olsson H, Su T, Memeo L, Ludwig T, Ethier SP, Krogh M, Szabolcs M, Murty VV, Isola J, Hibshoosh H, Parsons R, Borg A
Nature genetics 2008 Jan;40(1):102-7