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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Immunocytochemistry [1]
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- Product number
- ALX-804-254-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#ALX-804-254-C100, RRID:AB_2052425
- Product name
- PTEN monoclonal antibody (6H2.1)
- Antibody type
- Monoclonal
- Antigen
- Recombinant full length protein
- Description
- Protein A-affinity purified. Sterile filtered.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 6H2.1
- Vial size
- 100 μg
- Storage
- -20°C
Submitted references Molecular identification of latent precancers in histologically normal endometrium.
Changes in endometrial PTEN expression throughout the human menstrual cycle.
Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers.
Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast.
PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death.
Mutter GL, Ince TA, Baak JP, Kust GA, Zhou XP, Eng C
Cancer research 2001 Jun 1;61(11):4311-4
Cancer research 2001 Jun 1;61(11):4311-4
Changes in endometrial PTEN expression throughout the human menstrual cycle.
Mutter GL, Lin MC, Fitzgerald JT, Kum JB, Eng C
The Journal of clinical endocrinology and metabolism 2000 Jun;85(6):2334-8
The Journal of clinical endocrinology and metabolism 2000 Jun;85(6):2334-8
Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers.
Mutter GL, Lin MC, Fitzgerald JT, Kum JB, Baak JP, Lees JA, Weng LP, Eng C
Journal of the National Cancer Institute 2000 Jun 7;92(11):924-30
Journal of the National Cancer Institute 2000 Jun 7;92(11):924-30
Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast.
Perren A, Weng LP, Boag AH, Ziebold U, Thakore K, Dahia PL, Komminoth P, Lees JA, Mulligan LM, Mutter GL, Eng C
The American journal of pathology 1999 Oct;155(4):1253-60
The American journal of pathology 1999 Oct;155(4):1253-60
PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death.
Weng LP, Smith WM, Dahia PL, Ziebold U, Gil E, Lees JA, Eng C
Cancer research 1999 Nov 15;59(22):5808-14
Cancer research 1999 Nov 15;59(22):5808-14
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Supportive validation
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- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Left) PTEN non-expressing neoplastic endometrial glands in a background of normal expressing glands and stroma. Right) Single band specificity of MAb to PTEN 6H2.1 on PTEN expressing cancer cell lines.
