BS4748

antibody from Bioworld Technology, Inc

Targeting: EIF4E EIF4E1, EIF4EL1, EIF4F

Immunohistochemistry

Antibody data

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Validation data

Product number: BS4748 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS4748, RRID:AB_1663147
Product name: eIF4E (phospho S209) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic phosphopeptide derived from human eIF4E around the phosphorylation site of Serine 209.
Description: eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

EIF4E protein structure - BS4748 shown in red.