Ab175653

antibody from Aladdin Scientific Corporation

Targeting: ERBB3 HER3, LCCS2

ELISA (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Functional assay (Data presented on provider website)

Antibody Data

Product number

Ab175653

Provider

Aladdin Scientific Corporation

Product name

Seribantumab (anti-ERBB3)

Antibody type

Recombinant

Description

Seribantumab (anti-ERBB3) is a fully human IgG2 monoclonal antibody that targets HER3. Seribantumab (anti-ERBB3) blocks the activation of epidermal growth factor receptor (ErbB) family members and its downstream signal. Seribantumab (anti-ERBB3) inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models.

Reactivity

Human, Mouse

Conjugate

Unconjugated

Vial size

10mg,1mg,5mg

Concentration

Lot by Lot

Storage

Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.