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Protein structure
PPOX
Protoporphyrinogen oxidasePPO, VP
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Novus Biologicals |  H00005498-M01 |
3 references | Monoclonal |
WB
EL
IHC
BN
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| LSBio | LS-C133391 |
Monoclonal |
WB
EL
IHC
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| Invitrogen Antibodies | PA5-112665 |
Polyclonal |
WB
EL
ICC
IP
IHC
OA
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| Abnova Corporation | H00005498-M01 |
3 references | Monoclonal |
WB
EL
IHC
|
|
| Proteintech Group | 14870-1-AP |
1 references | Polyclonal |
WB
EL
IHC
|
|
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