Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- NB100-2258 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-2258, RRID:AB_2236074
- Product name
- Rabbit Polyclonal XLF Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references PHF6 promotes non-homologous end joining and G2 checkpoint recovery.
Clinical variability and novel mutations in the NHEJ1 gene in patients with a Nijmegen breakage syndrome-like phenotype.
Interplay between Cernunnos-XLF and nonhomologous end-joining proteins at DNA ends in the cell.
Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells.
Warmerdam DO, Alonso-de Vega I, Wiegant WW, van den Broek B, Rother MB, Wolthuis RM, Freire R, van Attikum H, Medema RH, Smits VA
EMBO reports 2020 Jan 7;21(1):e48460
EMBO reports 2020 Jan 7;21(1):e48460
Clinical variability and novel mutations in the NHEJ1 gene in patients with a Nijmegen breakage syndrome-like phenotype.
Dutrannoy V, Demuth I, Baumann U, Schindler D, Konrat K, Neitzel H, Gillessen-Kaesbach G, Radszewski J, Rothe S, Schellenberger MT, Nürnberg G, Nürnberg P, Teik KW, Nallusamy R, Reis A, Sperling K, Digweed M, Varon R
Human mutation 2010 Sep;31(9):1059-68
Human mutation 2010 Sep;31(9):1059-68
Interplay between Cernunnos-XLF and nonhomologous end-joining proteins at DNA ends in the cell.
Wu PY, Frit P, Malivert L, Revy P, Biard D, Salles B, Calsou P
The Journal of biological chemistry 2007 Nov 2;282(44):31937-43
The Journal of biological chemistry 2007 Nov 2;282(44):31937-43
Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells.
Zha S, Alt FW, Cheng HL, Brush JW, Li G
Proceedings of the National Academy of Sciences of the United States of America 2007 Mar 13;104(11):4518-23
Proceedings of the National Academy of Sciences of the United States of America 2007 Mar 13;104(11):4518-23
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: XLF Antibody [NB100-2258] - Detection of Human XLF on HeLa whole cell lysate using NB100-2258. XLF was also immunoprecipitated using rabbit anti-XLF antibody NB100-2257.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: XLF Antibody [NB100-2258] - Section of human breast carcinoma. Antibody: Affinity purified rabbit anti- XLF used at a dilution of 1:200 (1ug/ml). Detection: DAB