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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- PAB4685 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4685, RRID:AB_1571191
- Product name
- ACE2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of ACE2.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references The novel angiotensin-converting enzyme (ACE) homolog, ACE2, is selectively expressed by adult Leydig cells of the testis.
ACE2: from vasopeptidase to SARS virus receptor.
ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis.
Douglas GC, O'Bryan MK, Hedger MP, Lee DK, Yarski MA, Smith AI, Lew RA
Endocrinology 2004 Oct;145(10):4703-11
Endocrinology 2004 Oct;145(10):4703-11
ACE2: from vasopeptidase to SARS virus receptor.
Turner AJ, Hiscox JA, Hooper NM
Trends in pharmacological sciences 2004 Jun;25(6):291-4
Trends in pharmacological sciences 2004 Jun;25(6):291-4
ACE2 X-ray structures reveal a large hinge-bending motion important for inhibitor binding and catalysis.
Towler P, Staker B, Prasad SG, Menon S, Tang J, Parsons T, Ryan D, Fisher M, Williams D, Dales NA, Patane MA, Pantoliano MW
The Journal of biological chemistry 2004 Apr 23;279(17):17996-8007
The Journal of biological chemistry 2004 Apr 23;279(17):17996-8007
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of HL-60 cell lysate (35 ug/lane) with ACE2 polyclonal antibody (Cat # PAB4685).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with ACE2 polyclonal antibody (Cat # PAB4685) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Flow cytometric analysis of HL-60 cells using ACE2 polyclonal antibody (Cat # PAB4685)(bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
- Validation comment
- Flow Cytometry
