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- Antibody Data
- Antigen structure
- References [21]
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- Validations
- Western blot [1]
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- Product number
- 20384-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20384-1-AP, RRID:AB_10697662
- Product name
- NPHS2 antibody
- Antibody type
- Polyclonal
- Description
- NPHS2 antibody (Cat. #20384-1-AP) is a rabbit polyclonal antibody that shows reactivity with mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Podocyte-specific Crb2 knockout mice develop focal segmental glomerulosclerosis.
Experimental study on renoprotective effect of intermedin on diabetic nephropathy.
Carnosine alleviates podocyte injury in diabetic nephropathy by targeting caspase-1-mediated pyroptosis.
A Technique for Studying Glomerular Filtration Integrity in the Zebrafish Pronephros.
Adriamycin does not damage podocytes of zebrafish larvae.
Paecilomyces cicadae-fermented Radix astragali activates podocyte autophagy by attenuating PI3K/AKT/mTOR pathways to protect against diabetic nephropathy in mice.
An integrated transcriptomics and network pharmacology approach to exploring the mechanism of adriamycin-induced kidney injury.
Prolonged podocyte depletion in larval zebrafish resembles mammalian focal and segmental glomerulosclerosis.
Plakoglobin is involved in cytoskeletal rearrangement of podocytes under the regulation of UCH-L1.
Exploration the active compounds of Astragali Radix in treatment of adriamycin nephropathy by network pharmacology combined with transcriptomic approach.
Constructing an Isogenic 3D Human Nephrogenic Progenitor Cell Model Composed of Endothelial, Mesenchymal, and SIX2-Positive Renal Progenitor Cells.
MiR-320a induces diabetic nephropathy via inhibiting MafB.
Inhibiting 4E-BP1 re-activation represses podocyte cell cycle re-entry and apoptosis induced by adriamycin.
Critical roles of PI3K/Akt/NF‑κB survival axis in angiotensin II‑induced podocyte injury.
Fractalkine is Involved in Lipopolysaccharide-Induced Podocyte Injury through the Wnt/β-Catenin Pathway in an Acute Kidney Injury Mouse Model.
Expression and distribution of PIEZO1 in the mouse urinary tract.
Weighted Gene Correlation Network Analysis (WGCNA) Detected Loss of MAGI2 Promotes Chronic Kidney Disease (CKD) by Podocyte Damage.
Nestin Improves Preeclampsia-Like Symptoms by Inhibiting Activity of Cyclin-Dependent Kinase 5.
Response of Renal Podocytes to Excessive Hydrostatic Pressure: a Pathophysiologic Cascade in a Malignant Hypertension Model.
Acute podocyte injury is not a stimulus for podocytes to migrate along the glomerular basement membrane in zebrafish larvae.
Effects of asiaticoside on levels of podocyte cytoskeletal proteins and renal slit diaphragm proteins in adriamycin-induced rat nephropathy.
Tanoue A, Katayama K, Ito Y, Joh K, Toda M, Yasuma T, D'Alessandro-Gabazza CN, Kawachi H, Yan K, Ito M, Gabazza EC, Tryggvason K, Dohi K
Scientific reports 2021 Oct 15;11(1):20556
Scientific reports 2021 Oct 15;11(1):20556
Experimental study on renoprotective effect of intermedin on diabetic nephropathy.
Wang Y, Tian J, Mi Y, Ren X, Lian S, Kang J, Wang J, Zang H, Wu Z, Yang J, Qiao X, Zhou X, Wang G, Zhou Y, Li R
Molecular and cellular endocrinology 2021 May 15;528:111224
Molecular and cellular endocrinology 2021 May 15;528:111224
Carnosine alleviates podocyte injury in diabetic nephropathy by targeting caspase-1-mediated pyroptosis.
Zhu W, Li YY, Zeng HX, Liu XQ, Sun YT, Jiang L, Xia LL, Wu YG
International immunopharmacology 2021 Dec;101(Pt B):108236
International immunopharmacology 2021 Dec;101(Pt B):108236
A Technique for Studying Glomerular Filtration Integrity in the Zebrafish Pronephros.
Kolatsi-Joannou M, Osborn D
Methods in molecular biology (Clifton, N.J.) 2020;2067:25-39
Methods in molecular biology (Clifton, N.J.) 2020;2067:25-39
Adriamycin does not damage podocytes of zebrafish larvae.
Schindler M, Blumenthal A, Moeller MJ, Endlich K, Endlich N
PloS one 2020;15(11):e0242436
PloS one 2020;15(11):e0242436
Paecilomyces cicadae-fermented Radix astragali activates podocyte autophagy by attenuating PI3K/AKT/mTOR pathways to protect against diabetic nephropathy in mice.
Yang F, Qu Q, Zhao C, Liu X, Yang P, Li Z, Han L, Shi X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110479
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110479
An integrated transcriptomics and network pharmacology approach to exploring the mechanism of adriamycin-induced kidney injury.
He S, Li A, Zhang W, Zhang L, Liu Y, Li K, Qin X
Chemico-biological interactions 2020 Jul 1;325:109096
Chemico-biological interactions 2020 Jul 1;325:109096
Prolonged podocyte depletion in larval zebrafish resembles mammalian focal and segmental glomerulosclerosis.
Hansen KUI, Siegerist F, Daniel S, Schindler M, Iervolino A, Blumenthal A, Daniel C, Amann K, Zhou W, Endlich K, Endlich N
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):15961-15974
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):15961-15974
Plakoglobin is involved in cytoskeletal rearrangement of podocytes under the regulation of UCH-L1.
Fang Y, Li F, Qi C, Mao X, Xu Y, Zhao Z, Wu H, Zhang Z
Biochemical and biophysical research communications 2020 Aug 13;529(1):112-118
Biochemical and biophysical research communications 2020 Aug 13;529(1):112-118
Exploration the active compounds of Astragali Radix in treatment of adriamycin nephropathy by network pharmacology combined with transcriptomic approach.
Li AP, He SS, Zhang WN, Zhang LC, Liu YT, Li K, Qin XM
Journal of ethnopharmacology 2020 Aug 10;258:112537
Journal of ethnopharmacology 2020 Aug 10;258:112537
Constructing an Isogenic 3D Human Nephrogenic Progenitor Cell Model Composed of Endothelial, Mesenchymal, and SIX2-Positive Renal Progenitor Cells.
Nguyen L, Spitzhorn LS, Adjaye J
Stem cells international 2019;2019:3298432
Stem cells international 2019;2019:3298432
MiR-320a induces diabetic nephropathy via inhibiting MafB.
He M, Wang J, Yin Z, Zhao Y, Hou H, Fan J, Li H, Wen Z, Tang J, Wang Y, Wang DW, Chen C
Aging 2019 May 17;11(10):3055-3079
Aging 2019 May 17;11(10):3055-3079
Inhibiting 4E-BP1 re-activation represses podocyte cell cycle re-entry and apoptosis induced by adriamycin.
Li F, Mao X, Zhuang Q, Zhao Z, Zhang Z, Wu H
Cell death & disease 2019 Mar 11;10(3):241
Cell death & disease 2019 Mar 11;10(3):241
Critical roles of PI3K/Akt/NF‑κB survival axis in angiotensin II‑induced podocyte injury.
Wang J, Fu D, Senouthai S, You Y
Molecular medicine reports 2019 Dec;20(6):5134-5144
Molecular medicine reports 2019 Dec;20(6):5134-5144
Fractalkine is Involved in Lipopolysaccharide-Induced Podocyte Injury through the Wnt/β-Catenin Pathway in an Acute Kidney Injury Mouse Model.
Senouthai S, Wang J, Fu D, You Y
Inflammation 2019 Aug;42(4):1287-1300
Inflammation 2019 Aug;42(4):1287-1300
Expression and distribution of PIEZO1 in the mouse urinary tract.
Dalghi MG, Clayton DR, Ruiz WG, Al-Bataineh MM, Satlin LM, Kleyman TR, Ricke WA, Carattino MD, Apodaca G
American journal of physiology. Renal physiology 2019 Aug 1;317(2):F303-F321
American journal of physiology. Renal physiology 2019 Aug 1;317(2):F303-F321
Weighted Gene Correlation Network Analysis (WGCNA) Detected Loss of MAGI2 Promotes Chronic Kidney Disease (CKD) by Podocyte Damage.
Zuo Z, Shen JX, Pan Y, Pu J, Li YG, Shao XH, Wang WP
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(1):244-261
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(1):244-261
Nestin Improves Preeclampsia-Like Symptoms by Inhibiting Activity of Cyclin-Dependent Kinase 5.
Yang X, Ding Y, Yang M, Yu L, Hu Y, Deng Y
Kidney & blood pressure research 2018;43(2):616-627
Kidney & blood pressure research 2018;43(2):616-627
Response of Renal Podocytes to Excessive Hydrostatic Pressure: a Pathophysiologic Cascade in a Malignant Hypertension Model.
Abu Hamad R, Berman S, Hachmo Y, Stark M, Hasan F, Doenyas-Barak K, Efrati S
Kidney & blood pressure research 2017;42(6):1104-1118
Kidney & blood pressure research 2017;42(6):1104-1118
Acute podocyte injury is not a stimulus for podocytes to migrate along the glomerular basement membrane in zebrafish larvae.
Siegerist F, Blumenthal A, Zhou W, Endlich K, Endlich N
Scientific reports 2017 Mar 2;7:43655
Scientific reports 2017 Mar 2;7:43655
Effects of asiaticoside on levels of podocyte cytoskeletal proteins and renal slit diaphragm proteins in adriamycin-induced rat nephropathy.
Wang Z, Liu J, Sun W
Life sciences 2013 Sep 3;93(8):352-8
Life sciences 2013 Sep 3;93(8):352-8
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse colon tissue were subjected to SDS PAGE followed by western blot with 20384-1-AP(NPHS2 antibody) at dilution of 1:400
- Sample type
- tissue
