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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Flow cytometry [1]
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- Product number
- 361102 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#361102, RRID:AB_2562969
- Product name
- Purified anti-human/mouse/rat MR1
- Antibody type
- Monoclonal
- Antigen
- Soluble complexes of MR1 ectodomain and B2M.
- Description
- MHC-related protein 1, also known as MR1, is a nonclassical MHC class I molecule highly conserved in mammals, particularly in its α1/α2 domains. MR1 is required for the development and expansion of the mucosal-associated invariant T (MAIT) cells. The transcripts for MR1 are ubiquitously expressed, but its expression on the cell surface seems to be ligand-dependent. MR1 is involved in the presentation of vitamin-derived compounds from bacterial biosynthetic pathways.
- Reactivity
- Human, Mouse, Rat, Bovine
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- 26.5
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Human MR1-transfected Hela cells were stained with purified MR1 (clone 26.5, filled histogram) or purified mouse IgG2a, κ isotype control (open histogram), followed by anti-mouse IgG PE.
- Conjugate
- Unconjugated
