Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- NB100-1471 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-1471, RRID:AB_2219518
- Product name
- Goat Polyclonal MRP4/ABCC4 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. This antibody is expected to recognize isoform 1 (NP_005836.2) only.
- Reactivity
- Human, Mouse, Rat
- Host
- Goat
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Sensitizing gastric adenocarcinoma to chemotherapy by pharmacological manipulation of drug transporters.
Lactation during cholestasis: Role of ABC proteins in bile acid traffic across the mammary gland.
HEK-293 cells expressing the cystic fibrosis transmembrane conductance regulator (CFTR): a model for studying regulation of Cl- transport.
Developmental expression of renal organic anion transporters in rat kidney and its effect on renal secretion of phenolsulfonphthalein.
Effects of chronic renal failure on brain drug transporters in rats.
Effects of chronic renal failure on kidney drug transporters and cytochrome P450 in rats.
Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression.
Multidrug resistance protein 4 mediates cAMP efflux from rat preglomerular vascular smooth muscle cells.
MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs.
Al-Abdulla R, Perez-Silva L, Lozano E, Macias RIR, Herraez E, Abad M, Segues N, Bujanda L, Briz O, Marin JJG
Biochemical pharmacology 2020 Jan;171:113682
Biochemical pharmacology 2020 Jan;171:113682
Lactation during cholestasis: Role of ABC proteins in bile acid traffic across the mammary gland.
Blazquez AMG, Macias RIR, Cives-Losada C, de la Iglesia A, Marin JJG, Monte MJ
Scientific reports 2017 Aug 7;7(1):7475
Scientific reports 2017 Aug 7;7(1):7475
HEK-293 cells expressing the cystic fibrosis transmembrane conductance regulator (CFTR): a model for studying regulation of Cl- transport.
Domingue JC, Ao M, Sarathy J, George A, Alrefai WA, Nelson DJ, Rao MC
Physiological reports 2014 Sep 1;2(9)
Physiological reports 2014 Sep 1;2(9)
Developmental expression of renal organic anion transporters in rat kidney and its effect on renal secretion of phenolsulfonphthalein.
Nomura M, Motohashi H, Sekine H, Katsura T, Inui K
American journal of physiology. Renal physiology 2012 Jun 15;302(12):F1640-9
American journal of physiology. Renal physiology 2012 Jun 15;302(12):F1640-9
Effects of chronic renal failure on brain drug transporters in rats.
Naud J, Laurin LP, Michaud J, Beauchemin S, Leblond FA, Pichette V
Drug metabolism and disposition: the biological fate of chemicals 2012 Jan;40(1):39-46
Drug metabolism and disposition: the biological fate of chemicals 2012 Jan;40(1):39-46
Effects of chronic renal failure on kidney drug transporters and cytochrome P450 in rats.
Naud J, Michaud J, Beauchemin S, Hébert MJ, Roger M, Lefrancois S, Leblond FA, Pichette V
Drug metabolism and disposition: the biological fate of chemicals 2011 Aug;39(8):1363-9
Drug metabolism and disposition: the biological fate of chemicals 2011 Aug;39(8):1363-9
Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression.
Xu S, Weerachayaphorn J, Cai SY, Soroka CJ, Boyer JL
American journal of physiology. Gastrointestinal and liver physiology 2010 Jul;299(1):G126-35
American journal of physiology. Gastrointestinal and liver physiology 2010 Jul;299(1):G126-35
Multidrug resistance protein 4 mediates cAMP efflux from rat preglomerular vascular smooth muscle cells.
Cheng D, Ren J, Jackson EK
Clinical and experimental pharmacology & physiology 2010 Feb;37(2):205-7
Clinical and experimental pharmacology & physiology 2010 Feb;37(2):205-7
MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs.
Schuetz JD, Connelly MC, Sun D, Paibir SG, Flynn PM, Srinivas RV, Kumar A, Fridland A
Nature medicine 1999 Sep;5(9):1048-51
Nature medicine 1999 Sep;5(9):1048-51
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Supportive validation
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- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MRP4/ABCC4 Antibody [NB100-1471] - Staining Human Prostate tissue. Antibody at 4 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.