Antibody data

Product number
BS60498 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ATP6V1G3 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human ATP6V1G3.
Description
Vacuolar-type H+-ATPase (V-ATPase) is a multisubunit enzyme responsible for acidification of eukaryotic intracellular organelles. V-ATPases pump protons against an electrochemical gradient, while F-ATPases reverse the process, thereby synthesizing ATP. A peripheral V1 domain, which is responsible for ATP hydrolysis, and a integral V0 domain, which is responsible for proton translocation, compose V-ATPase. Nine subunits (AÿH) make up the V1 domain and five subunits (a, d, c, c' and c") make up the V0 domain. Like F-ATPase, V-ATPase most likely operates through a rotary mechanism. In yeast, the V-ATPase G subunit is a soluble subunit that shares homology with the F-ATPase G subunit and may be part of a connection stalk between V1 and V0. The G2 isoform of the G subunit associates with the pore-forming a1C-subunit of L-type calcium channel and aids in proper membrane targeting of the calcium channel. The genes encoding the G1 and G2 V-ATPase subunits map to chromosomes 9q33.1 and 6p21.3, respectively.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ATP6V1G3 protein structure - BS60498 shown in red.