CABT-B1395

antibody from Creative Diagnostics

Targeting: PER2 KIAA0347

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B1395

Provider

Creative Diagnostics

Product name

Anti-PER2 monoclonal antibody, clone 8I5.2

Antibody type

Monoclonal

Description

Period circadian protein homolog 2 (PER2), or Circadian clock protein PERIOD2, is a component of the circadian clock mechanism which is essential for generating circadian rhythms. It is a negative element in the circadian transcriptional loop by Influencing clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. PER2 negatively regulates CLOCK NPAS2-BMAL1 BMAL2-induced transactivation. This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG