Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 15117-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15117-1-AP, RRID:AB_2136682
- Product name
- LMOD1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated LMOD1 antibody (Cat. #15117-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Prime editing in mice reveals the essentiality of a single base in driving tissue-specific gene expression.
Putative Autoantigen Leiomodin-1 Is Expressed in the Human Brain and in the Membrane Fraction of Newly Formed Neurons.
Vascular smooth muscle-MAPK14 is required for neointimal hyperplasia by suppressing VSMC differentiation and inducing proliferation and inflammation.
Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus.
Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice.
Nodding syndrome may be an autoimmune reaction to the parasitic worm Onchocerca volvulus.
CRISPR-Cas9 genome editing of a single regulatory element nearly abolishes target gene expression in mice--brief report.
Gene Expression by Mouse Inner Ear Hair Cells during Development.
Identification and initial functional characterization of a human vascular cell-enriched long noncoding RNA.
Leiomodin 1, a new serum response factor-dependent target gene expressed preferentially in differentiated smooth muscle cells.
Gao P, Lyu Q, Ghanam AR, Lazzarotto CR, Newby GA, Zhang W, Choi M, Slivano OJ, Holden K, Walker JA 2nd, Kadina AP, Munroe RJ, Abratte CM, Schimenti JC, Liu DR, Tsai SQ, Long X, Miano JM
Genome biology 2021 Mar 16;22(1):83
Genome biology 2021 Mar 16;22(1):83
Putative Autoantigen Leiomodin-1 Is Expressed in the Human Brain and in the Membrane Fraction of Newly Formed Neurons.
Nauen DW, Haffner MC, Kim J, Zheng Q, Yin H, DeMarzo AM, Mahairaki V, Colantuoni C, Pickering JG, Johnson TP
Pathogens (Basel, Switzerland) 2020 Dec 10;9(12)
Pathogens (Basel, Switzerland) 2020 Dec 10;9(12)
Vascular smooth muscle-MAPK14 is required for neointimal hyperplasia by suppressing VSMC differentiation and inducing proliferation and inflammation.
Wu W, Zhang W, Choi M, Zhao J, Gao P, Xue M, Singer HA, Jourd'heuil D, Long X
Redox biology 2019 Apr;22:101137
Redox biology 2019 Apr;22:101137
Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus.
Nanda V, Wang T, Pjanic M, Liu B, Nguyen T, Matic LP, Hedin U, Koplev S, Ma L, Franzén O, Ruusalepp A, Schadt EE, Björkegren JLM, Montgomery SB, Snyder MP, Quertermous T, Leeper NJ, Miller CL
PLoS genetics 2018 Nov;14(11):e1007755
PLoS genetics 2018 Nov;14(11):e1007755
Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice.
Halim D, Wilson MP, Oliver D, Brosens E, Verheij JB, Han Y, Nanda V, Lyu Q, Doukas M, Stoop H, Brouwer RW, van IJcken WF, Slivano OJ, Burns AJ, Christie CK, de Mesy Bentley KL, Brooks AS, Tibboel D, Xu S, Jin ZG, Djuwantono T, Yan W, Alves MM, Hofstra RM, Miano JM
Proceedings of the National Academy of Sciences of the United States of America 2017 Mar 28;114(13):E2739-E2747
Proceedings of the National Academy of Sciences of the United States of America 2017 Mar 28;114(13):E2739-E2747
Nodding syndrome may be an autoimmune reaction to the parasitic worm Onchocerca volvulus.
Johnson TP, Tyagi R, Lee PR, Lee MH, Johnson KR, Kowalak J, Elkahloun A, Medynets M, Hategan A, Kubofcik J, Sejvar J, Ratto J, Bunga S, Makumbi I, Aceng JR, Nutman TB, Dowell SF, Nath A
Science translational medicine 2017 Feb 15;9(377)
Science translational medicine 2017 Feb 15;9(377)
CRISPR-Cas9 genome editing of a single regulatory element nearly abolishes target gene expression in mice--brief report.
Han Y, Slivano OJ, Christie CK, Cheng AW, Miano JM
Arteriosclerosis, thrombosis, and vascular biology 2015 Feb;35(2):312-5
Arteriosclerosis, thrombosis, and vascular biology 2015 Feb;35(2):312-5
Gene Expression by Mouse Inner Ear Hair Cells during Development.
Scheffer DI, Shen J, Corey DP, Chen ZY
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Apr 22;35(16):6366-80
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Apr 22;35(16):6366-80
Identification and initial functional characterization of a human vascular cell-enriched long noncoding RNA.
Bell RD, Long X, Lin M, Bergmann JH, Nanda V, Cowan SL, Zhou Q, Han Y, Spector DL, Zheng D, Miano JM
Arteriosclerosis, thrombosis, and vascular biology 2014 Jun;34(6):1249-59
Arteriosclerosis, thrombosis, and vascular biology 2014 Jun;34(6):1249-59
Leiomodin 1, a new serum response factor-dependent target gene expressed preferentially in differentiated smooth muscle cells.
Nanda V, Miano JM
The Journal of biological chemistry 2012 Jan 20;287(4):2459-67
The Journal of biological chemistry 2012 Jan 20;287(4):2459-67
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 15117-1-AP(LMOD1 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of A375 cells, using LMOD1 antibody 15117-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line